European Study of 3APS in Mild to Moderate Alzheimer's Disease Patients
- Conditions
- Alzheimer's Disease
- Registration Number
- NCT00217763
- Lead Sponsor
- Bellus Health Inc. - a GSK company
- Brief Summary
The purpose of this Phase 3 study is to evaluate the efficacy and safety of 3APS as an add-on therapy to most standard medication for Alzheimer's disease compared to placebo (inactive substance pill) in patients with mild to moderate Alzheimer's disease.
- Detailed Description
* Duration of treatment: 18 months
* 3 treatment arms:
Placebo and 2 different doses of active drug.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 930
Not provided
Not provided
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (48)
Memory Centre, Polycliniques Brull, CHU de Liège
🇧🇪Liege, Belgium
Memory Clinic University Hospital Gasthuisberg, Neurology Department
🇧🇪Leuven, Belgium
Memory Clinic UMC St Radboud - Alzheimer Centre
🇳🇱Nijmegen, Netherlands
University Hospital Antwerp - Neurology - Prof. Dr. Patrick Cras, MD, PhD
🇧🇪Edegem, Belgium
Dept. of Neurology and Alzheimer Center - Vrije Universiteit Medical Center
🇳🇱Amsterdam, Netherlands
Hôpital Pellegrin CHU de Bordeaux
🇫🇷Bordeaux, France
Centre Hospitalier Régional Universitaire de Lille
🇫🇷Lille, France
Middelheim Ziekenhuis Lindendreef
🇧🇪Antwerp, Belgium
Hôpital Sainte Marguerite Service de neuro-geriatrie
🇫🇷Marseille, France
Hôpital Gui de Chauliac - Service de Neurologie du Pr J. Touchon
🇫🇷Montpellier, France
Psychiatrische Universitätsklinik Heidelberg - Sektion für Gerontopsychiatrie - Gedächtnisambulanz
🇩🇪Heidelberg, Germany
Centre Mémoire de Ressources et de Recherche Hôpital Pasteur
🇫🇷Nice, France
CHU Reims- Hôpital Sébastopol-Service de médecine interne et Gérontologie Clinique
🇫🇷Reims, France
Hôpital Hôtel Dieu - Consultation de Gérontologie
🇫🇷Rennes, France
Hôpital BROCA
🇫🇷Paris, France
Gemeinschaftspraxis
🇩🇪Bochum (Langendreer), Germany
Arzneimittelforschung Leipzig GmbH
🇩🇪Leipzig, Germany
Abteilung für Geriatrische Psychiatrie - Zentralinstitut für seelische Gesundheit - Universität Heidelberg
🇩🇪Mannheim, Germany
IRCCS Centro San Giovanni di Dio- Fatebenefratelli
🇮🇹Brescia, Italy
Hospital Clínico San Carlos
🇪🇸Madrid, Spain
San Martino Hospital - Padiglione Specialita' Fondi
🇮🇹Genova, Italy
Dept. of Neurosciences TCR - University of Modena and Reggio Emilia
🇮🇹Modena, Italy
Universita' Cattolica del Sacro Cuore
🇮🇹Rome, Italy
Hospital Universitairo La Paz
🇪🇸Madrid, Spain
Enheten för klinisk Läkemedelsforskning - Minnesmottagningen - Karolinska Universitetssjukhuset - Huddinge
🇸🇪Stockholm, Sweden
Medisch Centrum Alkmaar
🇳🇱Alkmaar, Netherlands
Hospital Universitario Ramón y Cajal - Unidad de Geriatria
🇪🇸Madrid, Spain
Memory clinic - Uddevalla Hospital
🇸🇪Uddevalla, Sweden
Memory Assessment Centre - Moorgreen Hospital
🇬🇧Southampton, United Kingdom
Kingshill Research Centre - Victoria Hospital
🇬🇧Swindon, United Kingdom
Memory Clinic -Geriatric Centre - Academic Hospital
🇸🇪Uppsala, Sweden
Memory Clinic - Neuropsychology Center - University Hospital
🇨🇭Basel, Switzerland
Fundaciò ACE- Institut Català de Neurociències Aplicades
🇪🇸Barcelona, Spain
Research Institute for Care of Elderly - St Martin's Hospital
🇬🇧Bath, United Kingdom
Fylde Medical Clinic
🇬🇧Blackpool, United Kingdom
Glasgow Memory Clinic - Golden Jubilee National Hospital
🇬🇧Glasgow, United Kingdom
Murray Royal Hospital
🇬🇧Perth, United Kingdom
Hospital del Mar- Servicio de Neurologia
🇪🇸Barcelona, Spain
Hospital Santa Creu i Sant Pau, Servicio de Neurología, Unitad de Memoria
🇪🇸Barcelona, Spain
Unitat de Valoració de la Memòria i les Demències - Hospital Santa Caterina - Institut d'Assistència Sanitària
🇪🇸Girona, Spain
CHU Purpan
🇫🇷Toulouse, France
Charité Campus Benjamin Franklin - Universitätsmedizin Berlin - Klinik und Hochschulambulanz für Psychiatrie und Psychotherapie
🇩🇪Berlin, Germany
Klinik für Psychiatrie und Psychotherapie - University Hospital Hamburg-Eppendorf - Dept. of Psychiatry and Psychotherapy
🇩🇪Hamburg, Germany
Department of Neuroscience - Section of Neurology - University of Pisa
🇮🇹Pisa, Italy
Johann-Wolfgang Goethe-Universität - Klinik für Psychiatrie und Psychotherapie
🇩🇪Frankfurt, Germany
Neuropsychiatric Clinic - University Hospital MAS
🇸🇪Malmo, Sweden
Wales College of Medicine - Llandough Hospital
🇬🇧Cardiff, United Kingdom
Memory Assessment Centre
🇬🇧Blackpool, United Kingdom