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临床试验/NCT05918900
NCT05918900已完成不适用

Descriptive and Comparative Analyses of Malnutrition Screening in Internal Medicine

University Medicine Greifswald1 个研究点 分布在 1 个国家目标入组 323 人开始时间: 2023年6月5日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
323
试验地点
1
主要终点
Overall presence of malnutrition risk

研究概览

简要总结

The goal of this observational study is to study the presence and consequences of malnutrition risk in hospitalized internal medicine patients.

The main questions it aims to answer are:

  1. How many patients are at risk of malnutrition at admission?
  2. Is there a link between an existing malnutrition risk and nutrition therapy that the patients receive?
  3. Is there a link between an existing malnutrition risk and clinical outcome (e.g. length of hospital stay, mortality, need for rehospitalization)?

Participants will be screened for malnutrition risk at admission using a validated questionnaire (Nutritional Risk Screening 2002). All relevant data regarding hospital stay will be obtained from the clinical information system after discharge.

详细描述

Malnutrition is associated with adverse clinical outcome in hospitalized patients. Therefore, systematic screening for malnutrition risk at admission is recommended by almost all medical expert societies to identify patients who will benefit from nutritional therapy.

Although clinical and economic benefit of systematic malnutrition screening have been shown in various settings and for different patient groups, such screening is still not mandatory in most countries. In part, establishment of malnutrition screening is hampered by discrepant findings on the prevalence of malnutrition risk and the lack of evidence on a local level.

Hence, in this observational study the investigators examine the results of systematic malnutrition screening in internal medicine patients admitted to a university hospital in Northeast Germany. In particular, the investigators aim to determine the prevalence of malnutrition risk at hospital admission, the association between malnutrition risk and nutrition therapy as well as clinical outcome in different disciplines of internal medicine.

For this purpose, all patients undergo screening for malnutrition risk at admission using a validated instrument (Nutritional Risk Screening 2002). All relevant data regarding the patients' hospital stay will be obtained from the clinical information system after discharge.

研究设计

研究类型
Observational
观察模型
Other
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • hospital admission for gastrointestinal, endocrine, rheumatic, or nephrological condition
  • provision of informed consent

排除标准

  • inability to provide consent
  • unfeasibility to perform malnutrition screening within 48h after admission

结局指标

主要结局

Overall presence of malnutrition risk

时间窗: Baseline

Prevalence of malnutrition risk, i.e. Nutritional Risk Screening 2002 (NRS-2002) score \>= 3 points, in all internal medicine patients at hospital admission. NRS-2002 score ranges from 0 to 7, with higher values indicating greater nutritional risk.

次要结局

  • Presence of malnutrition risk in gastroenterology(Baseline)
  • Presence of malnutrition risk in rheumatology(Baseline)
  • Presence of malnutrition risk in nephrology(Baseline)
  • Relation of malnutrition risk to nutritional consultation(Baseline)
  • Relation of malnutrition risk to intermediate care treatment(Baseline)
  • Presence of malnutrition risk in endocrinology(Baseline)
  • Relation of malnutrition risk to nutritional diagnosis(Baseline)
  • Relation of malnutrition risk and 30-day readmission(Baseline)
  • Relation of malnutrition risk to intensive care treatment(Baseline)
  • Relation of malnutrition risk to mortality(Baseline)
  • Relation of malnutrition risk and 90-day readmission(Baseline)
  • Relation of malnutrition risk to length of hospital stay(Baseline)

研究者

发起方
University Medicine Greifswald
申办方类型
Other
责任方
Sponsor

研究点 (1)

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