Mobile phone SMS for adherence support for hypertension in South African adults in care for HIV infectio

Not Applicable

• Conditions: Circulatory System; HIV/AIDS

• Registration Number: PACTR201811878799717
• Lead Sponsor: South African Medical Research Council

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2018-11-19
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 1300

Inclusion Criteria

Patients will be included if the following are satisfied:
A) Diagnosed with HIV and Hypertension;
B) on ART and on blood pressure lowering medication (or about to start);
C) BP at recruitment >140/90 mmHg;
D) within 8 weeks of a viral load test (to offset the cost of baseline viral load and reduce the overall cost of the study);
E) accessing care for both HIV and hypertension at selected sites; F) have regular access to a mobile phone and able to access SMS text messages;
G) >18 years of age and willing to participate and give written informed consent.

Exclusion Criteria

A) requirering specialist care for hypertension;
B) self-reported pregnancy or within three months post-partum;
C) very high BP (systolic >220 mmHg or diastolic >120 mmHg) or symptoms suggestion hypertensive emergency;
D) Active malignancy or ongoing treatment for malignancy;
E) Acutely unwell patients.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Mean difference in systolic and diastolic blood Pressure

Secondary Outcome Measures

Name	Time	Method
1) uptake and adherence to BP medications, 2) uptake an adherence to HIV specific medications, 3) mean change in lipid variables, 4) mean change in CD4 count and viral load, 4) mean change in adiposity variables, 5) change in kidney function; Tertiary - 1) Descriptive analysis of the process involved in the intervention, 2) Economic analysis, 3) Quality of life.