Therapeutic effect of metformin in rectal cancer
Phase 2
Recruiting
- Conditions
- Rectal cancer.Malignant neoplasm of rectum
- Registration Number
- IRCT20190726044335N1
- Lead Sponsor
- Shiraz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 90
Inclusion Criteria
All non-diabetic patients with rectal adenocarcinoma aged 18 to 75 y/o and performance status <2
Exclusion Criteria
Treatment with surgery or radiation alone, distant metastasis, previous pelvic radiotherapy, and hypersensitivity reaction to the medications
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pathologic complete response. Timepoint: Post operation. Method of measurement: Pathologic examination.
- Secondary Outcome Measures
Name Time Method Side effects. Timepoint: Weekly during intervention course. Method of measurement: Radiation therapy oncology group toxicity criteria.