Establishing Pressures at the Esophagogastric Junction During Diaphragmatic Breathing Using High-resolution Esophageal Manometry
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- Mayo Clinic
- 入组人数
- 13
- 试验地点
- 1
- 主要终点
- Pressure at the esophagogastric junction
研究概览
简要总结
The goal of this study is to determine which position, maneuvers or combination thereof generates the highest pressure at the EGJ as assessed by high-resolution esophageal manometry and thus greater or more robust contraction of the diaphragm.
详细描述
This is a prospective, single-center study of adult (age ≥18 years) participants undergoing high-resolution esophageal manometry to assess the optimal method of diaphragmatic breathing. Included patients will complete two validated surveys, the Brief Esophageal Dysphagia Questionnaire (BEDQ) and the Gastroesophageal Reflux Disease Questionnaire (GERDQ). Patients will then undergo a standard protocol of supine and upright swallows with high-resolution manometry analyzed according to the Chicago Classification v4.0. After completion of the standard manometry protocol, participants will then perform a protocol assessing different techniques and positions for diaphragmatic breathing.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •patients undergoing high-resolution esophageal manometry
排除标准
- •prior esophageal or gastric surgery
- •chest tube
- •major concomitant illness
- •sinus disease precluding manometry placement
- •history of heavy alcohol or tobacco use
- •poor comprehension and/or fluency of English language
- •inability or unwillingness of individual to give written informed consent
研究组 & 干预措施
Diaphragmatic breathing protocol
All patients will undergo the diaphragmatic breathing protocol with high-resolution esophageal manometry.
干预措施: diaphragmatic breathing (Diagnostic Test)
结局指标
主要结局
Pressure at the esophagogastric junction
时间窗: Measured for each participant during high-resolution esophageal manometry. Data will be collected over the enrollment period of one year.
Measurement of EGJ- contractile integral and diaphragmatic pressure with each exercise/instruction
次要结局
未报告次要终点
研究者
Andree H. Koop
Principal Investigator
Mayo Clinic