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Clinical Trials/NCT01590212
NCT01590212
Completed
Not Applicable

Antenatal Parenting Support for Women Vulnerable in Pregnancy: an Exploratory Randomised Controlled Trial of Mellow Bumps

University of Glasgow2 sites in 1 country35 target enrollmentMay 2012

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Mental Health Wellness 1
Sponsor
University of Glasgow
Enrollment
35
Locations
2
Primary Endpoint
Depression Measured on EPDS
Status
Completed
Last Updated
12 years ago

Overview

Brief Summary

The purpose of this study is to compare the effectiveness of a relationships based antenatal intervention (Mellow Bumps) against a comparison intervention (Chillout In Pregnancy) and also against the normal antenatal care which is received during pregnancy (Care As Usual). The Mellow Bumps intervention will seek to improve maternal anxiety and maternal sensitivity whilst the Chillout In Pregnancy intervention will aim to improve only maternal anxiety. This will allow the researchers to determine what type of intervention, if any, is most successful at improving the outcomes of the mother and child. This will be measured by looking at the mother's stress response, anxiety, depression and irritability, the baby's stress response and the interactions between the mother and the baby. Participants in the study will be pregnant women who would be between 20 and 30 weeks pregnant at the start of the antenatal intervention. Participants will be chosen to take part in one of the three conditions (Mellow Bumps, Chillout In Pregnancy or Care As Usual) at random. All participants will be asked to complete questionnaires and give saliva samples prior to the intervention. The questionnaires will also be repeated at the end of the intervention and at a follow up occurring eight to twelve weeks after birth. Consent will also be sought to take saliva samples from the baby before and after a routine blood test when the baby is five days old. This information will then be evaluated to establish the effectiveness of the proposed interventions.

Detailed Description

Lower than anticipated recruitment numbers have resulted in changes to the planned methodology of this trial. Firstly, participants were allocated to the three arms in groups/blocks of 6. Secondly, randomisation of the final group recruited was abandoned.

Registry
clinicaltrials.gov
Start Date
May 2012
End Date
June 2013
Last Updated
12 years ago
Study Type
Interventional
Study Design
Parallel
Sex
Female

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Dr Philip Wilson

Professor of Primary Care and Rural Health

University of Aberdeen

Eligibility Criteria

Inclusion Criteria

  • pregnant, between 20 \& 30 weeks gestation at start of intervention
  • Identified by midwives as meeting Special Needs in Pregnancy (SNiP) criteria
  • basic understanding of written and spoken English

Exclusion Criteria

  • not identified as vulnerable through SNiP criteria
  • less than 20 weeks or more than 30 weeks gestation at start of intervention

Outcomes

Primary Outcomes

Depression Measured on EPDS

Time Frame: Post-birth (8-12 weeks postnatal)

Depression scores as measured on the EPDS post-birth (approximately 8-12 weeks postnatal) Edinburgh Postnatal Depression Scale (EPDS): is a standardised questionnaire which generates a single score. Normal score=0-9, Borderline=10-12, Probable depression=13-30.

Anxiety, Depression and Irritability Measured on Adult Wellbeing Scale

Time Frame: Post-birth (8-12 weeks postnatal)

Anxiety, depression and irritability measured on the Adult Wellbeing Scale post-birth (approximately 8-12 weeks postnatal) The Adult Wellbeing scale (AWS): a validated questionnaire which generates scores in four domains - depression, anxiety, outward-directed irritability and inward-directed irritability. The sub-scales have different cut-off scores that indicate a possible problem in that area: Anxiety (normal=0-5, borderline=6-8, problem 9-15), Depression (normal=0-3, borderline=4-6, problem 7-15), Outward directed irritability (normal=0-4, borderline=5-7, problem 8-12), Inward directed irritability (normal=0-3, borderline=4-6, problem 7-12),

Study Sites (2)

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