CTIS2024-515260-31-00进行中（未招募）1 期
proMoting Effective Renoprotection in Cardiac sURgery patients by Inhibition of SGLT-2
适应症
试验速览
- 阶段
- 1 期
- 状态
- 进行中（未招募）
- 入组人数
- 784
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 年龄范围
- 18 至 65+（—）
- 性别
- All
入选标准
- •> 18 years-old, Undergoing elective cardiac surgery with cardio-pulmonary bypass (CPB) or off-pump coronary artery bypass surgery (OPCAB)., Providing informed consent
排除标准
- •Current treatment with SGLT2 inhibitors, Reduced kidney function at baseline with eGFR < 20 ml/min at time of inclusion, Diabetes Mellitus Type 1, History of diabetic keto acidosis, Diabetes Mellitus Type 2 with BMI<25 for people with type 2 diabetes who are using multiple daily insulin injections (both short and long-acting insulin), Systolic blood pressure < 100 mmHg at time of inclusion, Emergency surgery, defined as in need of surgery for medical reasons < 7 days, i.e. S1- 4” according to the Amsterdam UMC classification, Female of child-bearing potential who is pregnant, breast-feeding or intend to become pregnant or is not using adequate contraceptive methods, Known or suspected allergy to trial products or other drugs in the same class
研究者
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