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Clinical Trials/NCT03453645
NCT03453645
Unknown
Not Applicable

Modification of Rhythmic Risk Assessment by Ventricular Tachycardia Ablation

University Hospital, Toulouse1 site in 1 country30 target enrollmentSeptember 9, 2017

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Ventricular Tachycardia
Sponsor
University Hospital, Toulouse
Enrollment
30
Locations
1
Primary Endpoint
measure assessing change before and after Ventricular Tachycardia Ablation of the non-invasive parameters analysis of the rhythmic risk before and after Ventricular Tachycardia Ablation
Last Updated
7 years ago

Overview

Brief Summary

Sudden cardiac death is a frequent cause of cardiovascular mortality. Numerous rhythmic risk assessment criterion have been described targeting the substratum, the cardiac nervous tone or the trigger of arrhythmias. Development of ventricular tachycardia ablation in the past few years show interesting results preventing the recurrence of ventricular arrhythmias.

Detailed Description

Sudden cardiac death is a frequent cause of cardiovascular mortality. Numerous rhythmic risk assessment criterion have been described targeting the substratum, the cardiac nervous tone or the trigger of arrhythmias. Development of ventricular tachycardia ablation in the past few years show interesting results preventing the recurrence of ventricular arrhythmias. Rhythmic risk assessment criterions have never been studied in relation with ventricular tachycardia ablation. The purpose of this study is to explore the modifications of these criterions after ventricular tachycardia ablation.

Registry
clinicaltrials.gov
Start Date
September 9, 2017
End Date
February 2019
Last Updated
7 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Patients undergoing ventricular tachycardia,
  • patients with ischemic cardiomyopathy according to European Society of Cardiology Guidelines,
  • patients with implanted cardiac defibrillator.

Exclusion Criteria

  • Contra-indication to stress test,
  • permanent atrial fibrillation,
  • permanent ventricular pacing,
  • left bundle block.

Outcomes

Primary Outcomes

measure assessing change before and after Ventricular Tachycardia Ablation of the non-invasive parameters analysis of the rhythmic risk before and after Ventricular Tachycardia Ablation

Time Frame: 10 minutes and 60 minutes after the Ventricular Tachycardia Ablation

non invasive parameters analysis of the rhythmic risk will be evaluated by the evaluation of the T wave alternans

Secondary Outcomes

  • Study of the correlation between the modifications of non-invasive parameters analysis of the rhythmic risk and the success of the ablation procedure(3 months, 6 months and 12 months after the Ventricular Tachycardia Ablation)
  • Assessing the correlations of the modifications of the risk criterion after ablation with the recurrences of arrhythmias at one year follow-up(3 months, 6 months and 12 months after the Ventricular Tachycardia Ablation)

Study Sites (1)

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