Omega-3 Fatty Acids Enriched Food and Microvascular Reactivity

Not Applicable

• Conditions: Omega-3 Polyunsaturated Fatty Acids

• Registration Number: NCT02720250
• Lead Sponsor: Josip Juraj Strossmayer University of Osijek

Brief Summary

Previous studies have shown that omega-3 fatty acid pills intake have beneficial effect on vascular health in overweight and/or hypertensive patients.

However, there is a lack of studies showing the effect of everyday consumption of omega-3 fatty acids enriched food (not pills) on lipid profile and microvascular reactivity in healthy population.

This study aimed to determine the effect of omega-3 enriched chicken eggs consumption on microvascular reactivity and lipid profile in young healthy subjects.

Detailed Description

Not available

Study Timeline

• Status Verified: 2016-03
• Study Start: 2016-03
• Study First Submitted: 2016-03-22
• Study First Submitted QC: 2016-03-24
• Study First Posted: 2016-03-25
• Last Update Submitted: 2016-03-29
• Last Update Posted: 2016-03-30
• Primary Completion: 2017-12
• Study Completion: 2018-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• healthy volunteers

Exclusion Criteria

• oral contraceptives
• drugs that could affect endothelium
• hypertension
• coronary artery disease
• diabetes
• hyperlipidaemia
• renal impairment
• cerebrovascular and peripheral artery disease

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
microvascular reactivity	Three weeks	Cutaneous microvascular blood flow will be measured by Laser Doppler Flowmetry in response to vascular occlusion (post occlusive reactive hyperaemia - PORH) and in response to iontophoresis of acetylcholine (ACh) (endothelium dependent vasodilation).

Secondary Outcome Measures

Name	Time	Method
lipid profile	Three weeks	Measurement of plasma cholesterol, HDL cholesterol, LDL cholesterol and triglycerides level.

Trial Locations

Locations (1)

Faculty of Medicine Osijek, Laboratory for Clinical and Sport Physiology; 🇭🇷 Osijek, Croatia