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Yang Yin Fu Zheng Therapy in HBV Associated Hepatocellular Carcinoma

Early Phase 1
Completed
Conditions
Hepatocellular Carcinoma
Interventions
Drug: Routine medical care
Drug: Yang Yin Fu Zheng therapy
Registration Number
NCT02927626
Lead Sponsor
Beijing Ditan Hospital
Brief Summary

Clinical research of Yang Yin Fu Zheng therapy in HBV associated hepatocellular carcinoma basing on immune microenviroment.The purpose of this study is to observe the efficacy of routine medical care combined with Yang Yin Fu Zheng therapy for patients belong to HBV-HCC.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
132
Inclusion Criteria
  1. Confirmed of stage HBV-HCCⅡb、Ⅲa、Ⅲb;
  2. Ages Eligible for Study: ≤75 years old;
  3. TCM syndrome is deficiency of both Qi and Yin;
  4. Confirmed of CHB;
  5. Surgery cannot be allowed;
  6. Informed consent from the patient.
Exclusion Criteria
  1. Patient with other chronic hepatopathy, such as AIH, NAFLD, ALD;
  2. Serious problem of heart, lung, or kidney with severe dysfunction;
  3. Pregnant or child breast feeding women;
  4. Mental or cognitive disorders;
  5. Participating in other drug trials;
  6. Who are allergic to the study drug.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Routine medical careRoutine medical care-
Yang Yin Fu Zheng therapyRoutine medical care-
Yang Yin Fu Zheng therapyYang Yin Fu Zheng therapy-
Primary Outcome Measures
NameTimeMethod
Survival rate2 years
Secondary Outcome Measures
NameTimeMethod
quality of life(QOL)2 years
Objective response rate2 years

Trial Locations

Locations (1)

Zhiyun Yang

🇨🇳

Beijing, Beijing, China

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