Role of Bilateral Repetitive Transcranial Magnetic Stimulation in Stroke Patients

Phase 3

Completed

• Conditions: Nervous System Diseases

• Registration Number: PACTR201907882363035
• Lead Sponsor: Dina Ahmed El Salmawy

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2019-03-22
• Last Update Posted: 2023-05-29

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 55

Inclusion Criteria

-Patients presenting by their first ischemic or hemorrhagic cerebrovascular stroke within >two weeks from onset so patients could have passed the flaccid stage and < six months duration of symptoms, as the best cortical plasticity is obtained in a period less than six months(Takeuchi et al., 2009).
-Subcortical hemispheric stroke confirmed by magnetic resonance imaging (MRI).
-Patients of a minor (1-4) to moderate (5-15) national institutes of health stroke scale score (Lyden, Lu & Levine, 2001) to allow patient to receive treatment and perform tests (Wolf Motor function test and Fugl Meyer assessment) to assess improvement with minimum assistance.
-No prior experience of rTMS to confirm blindness of the intervention

Exclusion Criteria

-Family history of epilepsy or patients who are known to be epileptic.
-Pregnant females.
-Convulsion after the stroke onset
-Patients with any medical metal devices incompatible with transcranial magnetic stimulation (pacemaker).
-Bi-hemispheric or multifocal stroke.
-Premorbid lower motor neuron impairment prior to the onset of stroke like peripheral neuropathy or radiculopathy.Other comorbidities as fracture or deformity.
-Patients with heart failure

Study & Design

• Study Type: Interventional
• Study Design: Not specified