Physical Activity and Its Impact on Colon Cancer Surgery: Clinical and Histological Effects
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Colon Cancer
- Sponsor
- Umeå University
- Enrollment
- 85
- Locations
- 1
- Primary Endpoint
- Number of postoperative complications
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
This is a prospective clinical study that studies how the physical activity level before operation of colon cancer affects the outcome of complication and histology.
The hypothesis is that patients who are more physical active have less postoperative complications and different histological immunological response around the tumor.
The investigators are testing the patients before the surgery with physical tests for fitness, strength and physical activity level. Questionnaires are also filled by the patients for pain, anxiety, depression and motivation for life style changes. Their body mass is analyzed with a DEXA (Dual-energy X-ray absorptiometry scan).
For one years the investigators are monitoring their activity and follow up for physical tests, DEXA and questionnaires is at 6 and 12 months.
The histology is analyzed after surgery to se if there is a different immunological response around the tumor.
Investigators
Eligibility Criteria
Inclusion Criteria
- •18 years.
- •Colon cancer which is going to surgery
Exclusion Criteria
- •Not able to do physical tests
- •Severe disease that makes a risk to do tests.
- •Not able to make informed consent due to psychic disease or dementia
Outcomes
Primary Outcomes
Number of postoperative complications
Time Frame: 1 year
To study if there are differences in postoperative complications in different active patients.
Rate of immunological response
Time Frame: 1 year
To study if there is a difference in immunological reaction among physical active patients.
Secondary Outcomes
- Rate of recovery in physical activity(1 year)