Physical Activity and Its Impact on Colon Cancer Surgery

Completed

• Conditions: Colon Cancer; Physical Activity

• Registration Number: NCT03947840
• Lead Sponsor: Umeå University

Brief Summary

This is a prospective clinical study that studies how the physical activity level before operation of colon cancer affects the outcome of complication and histology.

The hypothesis is that patients who are more physical active have less postoperative complications and different histological immunological response around the tumor.

The investigators are testing the patients before the surgery with physical tests for fitness, strength and physical activity level. Questionnaires are also filled by the patients for pain, anxiety, depression and motivation for life style changes. Their body mass is analyzed with a DEXA (Dual-energy X-ray absorptiometry scan).

For one years the investigators are monitoring their activity and follow up for physical tests, DEXA and questionnaires is at 6 and 12 months.

The histology is analyzed after surgery to se if there is a different immunological response around the tumor.

Detailed Description

Not available

Study Timeline

• Study Start: 2019-01-30
• Study First Submitted: 2019-05-09
• Study First Submitted QC: 2019-05-09
• Study First Posted: 2019-05-13
• Status Verified: 2024-02
• Primary Completion: 2024-02-20
• Study Completion: 2024-02-20
• Last Update Submitted: 2024-02-20
• Last Update Posted: 2024-02-21

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 85

Inclusion Criteria

• 18 years.
• Colon cancer which is going to surgery

Exclusion Criteria

• Not able to do physical tests
• Severe disease that makes a risk to do tests.
• Not able to make informed consent due to psychic disease or dementia

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Number of postoperative complications	1 year	To study if there are differences in postoperative complications in different active patients.
Rate of immunological response	1 year	To study if there is a difference in immunological reaction among physical active patients.

Secondary Outcome Measures

Name	Time	Method
Rate of recovery in physical activity	1 year	To study if physical active patients have a faster postoperative recovery

Trial Locations

Locations (1)

Region Vasterbotten, centre of surgery; 🇸🇪 Umeå, Vasterbotten, Sweden