Coronary Flow Reserve Changes After Semaglutide Treatment
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 122
- 试验地点
- 1
- 主要终点
- Number of patients who had acute coronary syndrome
研究概览
简要总结
The goal of this observational study is to learn about the effects of semaglutide to coronary artery flow in diabetic and non-diabetic patients. The main question it aims to answer is:
Does semaglutide enhance coronary artery flow in diabetic and non-diabetic patients?
Participants already planned taking semaglutide by an endocrine specialist as their treatment was assessed with CFR before and 3 months after.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 28 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients who were planned to start semaglutide.
排除标准
- •Ischemic heart disease
- •Previous stent implantation or coronary bypass
- •Heart failure
- •Cardiomyopathies
- •Inflammatory diseases
- •Autoimmune rheumatic disease
- •Chronic liver and renal insufficiency
结局指标
主要结局
Number of patients who had acute coronary syndrome
时间窗: From start of the study to 3 months after
Semaglutide is known for its beneficial effects on coronary vasculature. If a patient had myocardial infarction, this patient can no longer participate in study because the CFR ultimately changes.
次要结局
- Number of patients who can not lose weight(From start to 3 months)
研究者
Ekrem Bilal Karaayvaz
Assistant Professor
Istanbul University