A randomised, double blinded, crossover study of the influence of Metoprolol on exercise induced elevation of catecholamines in healthy subjects. - MEXICHO
- Conditions
- The medical condition to be investigated is heart failure, but this specific study is made on healthy volunteers to investigate the influence of metoprolol on exercise induced elevation of catecholamines.
- Registration Number
- EUCTR2008-001908-23-DK
- Lead Sponsor
- Rigshospitalet, Department of Clinical Pharmacology
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Recruiting
- Sex
- Male
- Target Recruitment
- 30
Male, age 20-30 years, non-smoker, BMI 20-25, no chronic diseases including asthma bronchiale and cardiovascular diseases of any kind. No injuries of muscoloskeleton, that prevents participants in performing a full maximal cardiopulmonary test.
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range
Following medical products during investigational periode:
asthma medication, heart medication, antihistamines, antipsycotics, NSAIDs, rifampicin, chinidine, glukocorticoides, abuse of any kind.
Allergy and/or intolerance to metoprololsuccinate. Allergy to lactose. Abnormal ECG. Abnormal bloodsugar according to standards.
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method