Detection of Arousal With Facial Micro-expression in Severe Brain-damaged Patient

Not Applicable

Terminated

• Conditions: Consciousness Disorder
• Interventions: Other: Detection of arousal

• Registration Number: NCT03023657
• Lead Sponsor: Centre Hospitalier Universitaire de Saint Etienne

Brief Summary

Severe brain injuries lead to disorders of consciousness after coma. During this awakening period, detection of arousal is critical to the adaptation of medical strategy, but global paralysis, including facial expression, make the clinical assessment very difficult. Emotional facial expressions are a significant part of this clinical assessment. They are both a landmark of the internal state of the patient (comfort versus discomfort) and a landmark of the relational level with his environment. Visible emotional facial expression is a large temporal phenomenon lasting a couple of seconds, while a microexpression is barely noticeable and very brief. These micro expressions are usually produced when one tried to voluntary hide emotional expressions. In this study, we hypothesize that some patients awakening from coma could still produce microexpression before being able to produce visible emotional facial expressions. This ability to produce micro-expression could be an early landmark of relational awakening in severe brain lesions.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2017-01-13
• Study First Submitted QC: 2017-01-13
• Study First Posted: 2017-01-18
• Study Start: 2017-06-23
• Primary Completion: 2017-10-16
• Study Completion: 2017-10-16
• Status Verified: 2022-09
• Last Update Submitted: 2022-09-12
• Last Update Posted: 2022-09-14

Recruitment & Eligibility

• Status: TERMINATED
• Sex: All
• Target Recruitment: 3

Inclusion Criteria

• Brain-damaged patient (stroke, traumatic brain injury, anoxia)
• Disorder of consciousness (CRS-R≤ 10) more than 48h after stopping sedation
• Patient without spontaneous or stimulated facial expressions

Exclusion Criteria

• Medically unstable patient

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Severe brain-damaged patient in coma awakening	Detection of arousal	For each patient, video sessions of the face will be performed during a waking period, until the spontaneous macro-EFE (Emotional Facial Expression) reappears. The video sessions will be done without stimulation or with visual, auditory or tactile stimulation. The sessions will be daily for 7 days then weekly for a maximum duration of 4 weeks.

Primary Outcome Measures

Name	Time	Method
facial micro expression found in at least one patient on one video recording	Every day for a week then once a week for four weeks	Optical camera and thermal camera

Trial Locations

Locations (2)

Chu Saint-Etienne; 🇫🇷 Saint Etienne, France

Clinique Mutualiste Saint Etienne; 🇫🇷 Saint Etienne, France