Efficacy of Perioperative Long-acting Anesthesia by Local Infiltration Following Median Sternotomy - The PAIN Trial - The PAIN Trial

Aarhus University Hospital0 个研究点目标入组 100 人开始时间: 2022年1月24日最近更新: 2024年6月3日

适应症

试验速览

暂无简介。

•Patients undergoing first-time, non-emergent coronary artery bypass grafting including harvest of the left internal mammary artery through a median sternotomy
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range 40
•F.1.3 Elderly (>=65 years) yes
•F.1.3.1 Number of subjects for this age range 60

•Emergent treatment (<24 hours)
•Prior sternotomy or cardiac surgery
•Concurrent heart surgery other than arrythmia surgery (i.e lung vein ablation and/or left appendage closure)
•Daily use of opioids within the last 6 month prior to enrollment
•Preoperative regular use of corticosteroids
•Known allergy or intolerance to any of the included drugs
•Woman of childbearing age without negative pregnancy test and nursing women
•Any known condition that might interfere with the used drugs
•Known impaired kidney function (defined as eGFR < 30 ml/min)
•Active participation in another interventional trial with potential impact on postoperative pain and/or respiratory function

发起方

Aarhus University Hospital