EUCTR2021-005886-41-DK
Active, Not Recruiting
Phase 1
Efficacy of Perioperative Long-acting Anesthesia by Local Infiltration Following Median Sternotomy - The PAIN Trial - The PAIN Trial
Aarhus University Hospital0 sites100 target enrollmentJanuary 24, 2022
ConditionsAcute postoperative pain after coronary bypass grafting surgery.MedDRA version: 20.1Level: LLTClassification code 10054711Term: Postoperative painSystem Organ Class: 100000004863Therapeutic area: Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Anesthesia and Analgesia [E03]
Overview
- Phase
- Phase 1
- Intervention
- Not specified
- Conditions
- Acute postoperative pain after coronary bypass grafting surgery.
- Sponsor
- Aarhus University Hospital
- Enrollment
- 100
- Status
- Active, Not Recruiting
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Patients undergoing first\-time, non\-emergent coronary artery bypass grafting including harvest of the left internal mammary artery through a median sternotomy
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1\.2 Adults (18\-64 years) yes
- •F.1\.2\.1 Number of subjects for this age range 40
- •F.1\.3 Elderly (\>\=65 years) yes
- •F.1\.3\.1 Number of subjects for this age range 60
Exclusion Criteria
- •Emergent treatment (\<24 hours)
- •Prior sternotomy or cardiac surgery
- •Concurrent heart surgery other than arrythmia surgery (i.e lung vein ablation and/or left appendage closure)
- •Daily use of opioids within the last 6 month prior to enrollment
- •Preoperative regular use of corticosteroids
- •Known allergy or intolerance to any of the included drugs
- •Woman of childbearing age without negative pregnancy test and nursing women
- •Any known condition that might interfere with the used drugs
- •Known impaired kidney function (defined as eGFR \< 30 ml/min)
- •Active participation in another interventional trial with potential impact on postoperative pain and/or respiratory function
Outcomes
Primary Outcomes
Not specified
Similar Trials
Not Yet Recruiting
N/A
Clinical study of impact of peri-operative anaesthetic management on early recovery after surgery (ERAS) for hepatic resections.Health Condition 1: K769- Liver disease, unspecifiedCTRI/2024/02/062799MAHATMA GANDHI MEDICAL COLLEGE AND HOSPITA
Active, Not Recruiting
N/A
Efficacy and safety of long term wound catheter infusion in patients undergoing mastectomy associated to breast reconstruction: a randomized, double-blind study.Post operative pain syndromesMedDRA version: 14.1Level: PTClassification code 10026878Term: MastectomySystem Organ Class: 10042613 - Surgical and medical proceduresTherapeutic area: Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Anesthesia and Analgesia [E03]EUCTR2011-006331-35-ITOSPEDALE POLICLINICO S. MATTEO
Not Yet Recruiting
N/A
To observe and compare the effects of anaesthesia, in patients who are undergoing surgery for removal of stones from the kidney in the supine and the prone position.CTRI/2022/02/040660Christian Medical College and hospital
Not Yet Recruiting
Phase 3
Effect of long acting anesthetic on pain during and after root canal treatmentHealth Condition 1: K044- Acute apical periodontitis of pulpal originCTRI/2023/11/060116Dr Apeksha Rao
Completed
N/A
Effects of the duration of local anesthetic administration for peripheral nerve block on postoperative pain control : A Randomized Controlled TrialJPRN-UMIN000012132Sapporo Medical University School of Medicine200