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Clinical Trials/NCT07272577
NCT07272577
Recruiting
Not Applicable

Efficacy of Erector Spinae Plane Block on Postoperative Analgesia in Patients Undergoing Laparoscopic Abdominal Surgeries

Assiut University1 site in 1 country50 target enrollmentStarted: December 10, 2025Last updated:

Overview

Phase
Not Applicable
Status
Recruiting
Enrollment
50
Locations
1
Primary Endpoint
Time to the 1st rescue analgesia

Overview

Brief Summary

This study aims to evaluate the efficacy of the erector spinae plane block (ESPB) on postoperative analgesia in patients undergoing laparoscopic abdominal surgeries.

Detailed Description

Laparoscopic surgery is associated with less pain, fewer wound infections, reduced hospital stay, reduced morbidity and mortality, and early return to work and improved overall quality of life.

The role of ESPB as a better analgesic modality in reducing 24-hour opioid consumption has recently been established for post-operative analgesia in breast surgeries, video-assisted thoracoscopic surgery, and cardiothoracic surgeries.

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel
Primary Purpose
Treatment
Masking
Double (Participant, Outcomes Assessor)

Eligibility Criteria

Ages
18 Years to — (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Age ≥ 18 years.
  • Both sexes.
  • American Society of Anesthesiologists (ASA) physical status I-II.
  • Body mass index (BMI) between 20-30 kg/m
  • Patients undergoing laparoscopic abdominal surgeries under general anesthesia.

Exclusion Criteria

  • Bleeding or coagulation disorders.
  • Having local sepsis, pre-existing.
  • Peripheral neuropathies.
  • Chronic pain conditions.
  • Having any contraindication to regional anesthesia administration.
  • Opioid dependency.
  • Hypertension.
  • Uncontrolled diabetes mellitus.

Outcomes

Primary Outcomes

Time to the 1st rescue analgesia

Time Frame: 24 hours postoperatively

Time to the first request for the rescue analgesia (time from the end of surgery to first dose of morphine administrated).

Secondary Outcomes

  • Total morphine consumption(24 hours postoperatively)
  • Mean arterial pressure(Till the end of surgery (Up to 2 hours))
  • Heart rate(Till the end of surgery (Up to 2 hours))
  • Degree of pain(24 hours postoperatively)
  • Incidence of adverse events(24 hours postoperatively)

Investigators

Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Bahaa Gamal Saad Mohamed

Anesthesia and Intensive Care, Faculty of Medicine, Assiut University, Assiut, Egypt.

Assiut University

Study Sites (1)

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