Early and mid-term outcomes of endovascular treatment for chronic aneurysmal aortic dissectio

Not Applicable

• Conditions: CAAD

• Registration Number: JPRN-UMIN000024525
• Lead Sponsor: Division of Vascular Surgery, Department of Surgery Jikei University School of Medicine

Brief Summary

Early outcomes No significant differences were observed between the two groups in terms of age, sex, duration from dissection onset to treatment, maximum short axis diameter of the CAAD, preoperative condition, and follow-up observation period, although the duration from dissection onset to treatment tended to be longer in the CE group than in the PE group. Operative death occurred in 1 out of 74 patients (1.4%); 2.3% in the PE group and 0% in CE group. Technical success in the PE and CE groups were 97.6% and 96.8%, respectively. The device most commonly used to perform entry closure was the TAG (W. L. Gore & Associates, Inc., Flagstaff AZ, USA), and no significant difference in the frequency of use was observed between the two groups. In the patient that died in the PE group, the tear in the arch could not be closed; therefore, the carotid artery was concomitantly reconstructed using the Chimney method. Furthermore, due to the fact that this patient previously underwent coronary artery bypass grafting using the left internal thoracic artery, the SG was extended proximally after creating a bypass from the left common carotid artery to the left subclavian artery. However, the entry site could not be completely closed and blood pressure decreased during surgery. Unfortunately, the patient died from cardiac failure on the same day due to prolonged hypotension. In one patient in the CE group, we attempted to close a renal artery tear, but a new intimal tear formed. In this case, conversion to open surgical repair was performed the next day and the patient was eventually discharged from the hospital without any major complications. In another patient in the CE group, no central nervous or spinal cord complications were observed, except for delayed paraplegia on postoperative day (POD) 2.

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2016-11-25
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Complete: follow-up continuing
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

Not provided

Exclusion Criteria

acute dissection

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
death paraplegia complete thrombosis of false lumen

Secondary Outcome Measures

Name	Time	Method
freedom from re-entry closure freedom from secondary intervention remodeling of aorta