Functional evaluation of neutrophil of patients at high risk for infection treated with multiple monocyte/ neutrophil aphaereses
Phase 1
- Conditions
- ulcerative colitis, large bowel perforation, esophageal cancer, colorectal cancer
- Registration Number
- JPRN-UMIN000013269
- Lead Sponsor
- Mie University Graduate School of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 10
Inclusion Criteria
Not provided
Exclusion Criteria
-patients with cardiovascular disease (acute myocardial infarction, ischemic heart disease, or arrhythmia requiring treatment within 6 months of onset) -with or with past histories of cerebral infarction or cerebrovascular disorder including intracerebral hemorrhage -patients with hypotension or systolic blood pressure of 80mmHg and under -pregnant or breast feeding women and women suspected of being pregnant -demented persons -patients with a histories of shock during extracorporeal circulation therapy -patients receiving angiotensin-converting enzyme inhibitors and inappropriate in these drugs withdrawal prior to apheresis -patients judged as inadequate for this study by attending physician
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Evaluation neutrophil function of patients at high risk for postoperative infection treated with monocyte/neutrophil apheresis
- Secondary Outcome Measures
Name Time Method Identification of frequency of blood apheresis needed for improvement in function of neutrophil