The benefits of Erythropoietin in reducing the need for blood transfusions in patients receiving chemotherapy

Phase 1

• Conditions: solid insitu tumor of the body.; In situ neoplasms; D00-D09

• Registration Number: IRCT2015061822805N1
• Lead Sponsor: Vice Chancellor for research of Tabriz University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Age of the patients, entering the study, should be beneath 15 years; The amount of Hemoglobin should be below 10 g/dL(gram per deciliter); Patients who are anemic due to chemotherapy, after they are diagnosed with solid insitu tumor; None of the patients have bone marrow involvement; Patients entering the study have normal kidney,liver,and lung function; Normal amounts of other blood-related parameters including retic.count, Serum ferritin, B12 vitamin in the serum, direct and indirect coombs tests, and ABG(Arterial Blood Gas); No history of blood transfusions in the last 1 month; No history of Erythropoietin consumption
Exclusion criteria: Severe bleeding during the study; Hemolysis during the study due to any causes; The evidence of existing imapirment in kidney,liver,and lung function; Evidence of any serious side effects of Erythropoietin including thrombosis, increased systemic blood pressure, and polycythemia

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The amount of hemoglobin increase. Timepoint: Weekly, until the end of the treatment. Method of measurement: g/dL(gram per deciliter) in blood tests.;The numbers and volume of blood transfusions. Timepoint: weekly blood test(hemoglobin amounts;transfusion of 10 ml/kg when hemoglobin is under 7 ml/dl). Method of measurement: Based on patients' hemoglobin and in mililiter.

Secondary Outcome Measures

Name	Time	Method
The numbers of referring to the clinic. Timepoint: weekly. Method of measurement: using their clinic files.