PACTR202404890252448RecruitingUnknown
A pilot pre- post trial of the feasibility, acceptability, tolerability, and efficacy of accelerated bilateral theta-burst stimulation for depression in adults with HIV in South Africa
Faculty of Medicine and Health Sciences0 sites10 target enrollmentStarted: March 28, 2024Last updated:
Trial Snapshot
- Phase
- Unknown
- Status
- Recruiting
- Enrollment
- 10
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional
Eligibility Criteria
- Ages
- 19 Year(s) to 44 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •Adults (= 18 years) diagnosed with HIV
- •On ART for an uninterrupted period of at least six months
- •Current comorbid MDD diagnosis confirmed by a diagnostic interview.
- •Able to attend the treatment and monitoring visits at the university campus during office hours.
- •Able to provide written informed consent.
- •For participants on psychotropic medication, a stable dose (=2 months) will be required before the pre-treatment assessment. These participants will continue with their current treatment regimens for the duration of their trial participation.
- •Participants will also be required not to engage in other interventions (i.e., psychotherapy) during the study
- •period (six weeks from pre-treatment to one-month follow-up).
Exclusion Criteria
- •Known with life-threatening medical illnesses (e.g., cancer), or serious psychiatric conditions (e.g., psychosis, mania).
- •Participants with specific TMS-associated contraindications (e.g., metal implants close to the skull area or uncontrolled epilepsy) will also be excluded.
Investigators
Similar Trials
Not yet recruiting
Phase 4
Point-of-care Urine Monitoring of Adherence (PUMA): Testing a Real-Time Urine Assay of Tenofovir in PrEPPACTR202003901399017niversity of California San Fransisco100
Completed
Not Applicable
Does cervical screening without a speculum increase screening uptake in women aged 50-64?Cervical screeningMalignant neoplasm of cervix uteriCancerISRCTN16007231King's College London700
Recruiting
Unknown
A pilot study to assess the feasibility and acceptability of a culturally adapted, ‘brief intervention’ vs ‘education about low risk drinking’ vs standard care for risky drinkers, in an outpatient setting in the Central Province, Sri Lanka.Alcohol use disordersSLCTR/2024/018Department of Psychiatry, Faculty of Medicine, University of Peradeniya
Completed
Not Applicable
mobile Pulmonary Rehabilitation - Determining the feasibility and acceptability of an adaptive mobile Pulmonary Rehabilitation (PR) programmeCOPDRespiratory ConditionsRespiratory - Chronic obstructive pulmonary diseaseRespiratory - Other respiratory disorders / diseasesACTRN12619000884101ational Institute for Health Innovation - University of Auckland30
Completed
Not Applicable
Dignity Therapy: A Psychotherapeutic Intervention to Enhance the End of Life Experience for Persons with Motor Neurone Disease and their Family CarersMotor Neurone DiseaseAmyotrophic Lateral SclerosisNeurological - Neurodegenerative diseasesACTRN12611000410954School of Psychology and Speech Pathology50