Brief Intervention in Primary Care for Problem Drug Use and Abuse
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 868
- 试验地点
- 2
- 主要终点
- Enrollment in formal substance abuse treatment
研究概览
简要总结
This study will examine the effectiveness of a brief intervention in a primary care setting to reduce drug use or abuse compared to enhanced care as usual.
详细描述
A substantial body of research has established the efficacy and effectiveness of brief interventions (BI) for excessive or "hazardous" alcohol use in patients seen in medical settings. Dissemination projects of brief interventions for alcohol and drugs have recently been implemented on a widespread scale. This rapid progression of brief intervention for drugs other than alcohol has outstripped its evidence base.
The aims of the study as outlined in the grant are:
- To examine whether BI is effective at improving outcomes (self-reported drug use and attendance in drug abuse treatment) in individuals with a wide range of problem drug use over and above enhanced care as usual. The enhanced control condition will consist of routine screening, patient notification, and referral for treatment.
- To test whether fidelity to the BI model or lower severity of drug use is associated with better outcomes.
- To estimate the impact of BI on several public health outcomes that are directly related to the hazardous effects of illicit drug use, including the use of acute health care services, involvement in the criminal justice system, employment, HIV risk behavior, and mortality.
- To estimate the costs of the intervention, potential cost offsets, and its incremental cost-effectiveness versus enhanced usual care from the payer perspective based on health care service use and drug use frequency.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •at least 18 years old
- •receive medical care at one of the participating primary care clinics at Harborview Medical Center/University of Washington Medical Center
- •will maintain care at the clinic for one year
- •have a phone or easy access to phone, voicemail, or email
- •used recreational drugs in the last 3 months
- •used prescription medications not as prescribed in the last 3 months
排除标准
- •participation in any formal substance abuse treatment programs in the last 30 days (excluding 12-step or self-help groups)
- •terminal illness
结局指标
主要结局
Enrollment in formal substance abuse treatment
时间窗: baseline up to 2 years post-intervention
Enrollment in formal substance abuse treatment will be measured as an admission to chemical dependency treatment as recorded in the Washington State TARGET database.
Use of illicit drugs in the past 30 days
时间窗: baseline, 3, 6, 9, and 12 months
Use of illicit drugs in the past 30 days will be measured by self-reported days of use in the past 30 days and validated by urine toxicological screen.
Medical, legal, employment, social, and psychiatric outcomes
时间窗: baseline, 3, 6, 9, and 12 months
Medical, legal, employment, social, and psychiatric outcomes will be measured by composite scores on the Addiction Severity Index (ASI) Lite.
次要结局
- Public health outcomes(baseline up to 2 years post-intervention)
- Cost of the intervention(baseline up to 2 years post-intervention)
- Incremental cost-effectiveness(baseline up to 2 years post-intervention)
研究者
Peter Roy-Byrne
Professor
University of Washington