NCT03759899Unknown不适用
Establishment of Clinical Applicable Human Amniotic Epithelial Cell Products and Its Preliminary Application in Allogeneic Hematopoietic Stem Cell Transplantation
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Cell counts of T cells, NK cells, B cells and monocytes
研究概览
简要总结
hAECs Are Preliminarily Applied in Allogeneic Hematopoietic Stem Cell Transplantation
详细描述
Establishment of Clinical Applicable Human Amniotic Epithelial Cell Products and Its Preliminary Application in Allogeneic Hematopoietic Stem Cell Transplantation
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •leukemia patients with allogeneic HSCT
- •KFS score >90
- •after transplantation, the patient was implanted (peripheral blood neutrophil absolute value >500/ul for 3 consecutive days)
- •no uncontrolled infection after transplantation
- •activity II above aGVHD
- •patients agreed to participate in the study
排除标准
- •patients refused to participate in the study
- •patients have poor compliance
- •has received hormone therapy
- •patients had serious heart, lung, liver, kidney and other vital organs damage
- •researchers believe that patients who are not suitable for observation study
结局指标
主要结局
Cell counts of T cells, NK cells, B cells and monocytes
时间窗: Day 7
proliferation and apoptosis of T cells, NK cells, B cells and monocytes in peripheral blood of patients
次要结局
未报告次要终点
研究者
Xiaojun Huang,MD
Director of the Hematology Department
Peking University People's Hospital
研究点 (1)
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