A study to compare the outcome of Umbilical Cord Serum as an adjuvant to Standard of Care alone in view of vision improvement,Dry eyes, healing in patients of Corneal disease.
- Conditions
- Health Condition 1: H578- Other specified disorders of eye and adnexa
- Registration Number
- CTRI/2022/11/046978
- Lead Sponsor
- Multi-Disciplinary Research Unit
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
1Ambulatory patients of either gender ï?³18 years at the time of screening after informed consent.
2 In acute corneal insult, PED and keratitis of duration less than 2 weeks.
1) Acute ocular injury requiring surgery, ocular perforation, infections, acute chemical injuries requiring
interventions and patients with poor visual prognosis, bedridden, debilitated or malignant patients.
2). Patients suffering from advance ocular diseases like advance glaucoma or advance retinal diseases
3). Patients who are not willing for complete workup or written consent.
4). Patients with active infective diseases like TB, herpes zoster etc.
5). Patients who are HIV, HBsAg, HCV test positive
6). Evidence of active infection in concern eye or in other eye.
7). Patients with no allergic reaction.
8). Presence of uncontrolled systolic blood pressure ï?³160mmHg or uncontrolled diastolic blood pressure ï?³
100mgHg.
9). Inability to obtain fundus photographs or Fluorescein angiograms of sufficient quality
10). Female subjects who are pregnant, breast feeding planning to be pregnant during the study
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Improvement in various clinical parameters dry eyes, healing/epithelialization, vision improvement and OSDI scoreTimepoint: 6-8 weeks
- Secondary Outcome Measures
Name Time Method Improvement in various clinical parameters dry eyes, healing/epithelialization, vision improvement and OSDI scoreTimepoint: 6 months