Prospective observational study of cancer-cachexia and its effect on chemotherapy in patients with previously-untreated advanced non-small cell lung cancer (NEJ050A)

Not Applicable

• Conditions: on-small cell lung cancer

• Registration Number: JPRN-UMIN000041813
• Lead Sponsor: orth East Japan Study Group (NEJSG)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2020-09-16
• Study Completion: 2022-09-30
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Complete: follow-up complete
• Sex: All
• Target Recruitment: 186

Inclusion Criteria

Not provided

Exclusion Criteria

(1) Current use of corticosteroids. (2) Subjects scheduled to receive treatment, but don't fit into cohorts 1, 2, or 3. (3) Subjects who are unable to accurately complete the QOL questionnaire. (4) Subjects who are judged by the principal or sub-investigator to be unsuitable for inclusion in this study.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Transition of FAACT (A/CS) during chemotherapy

Secondary Outcome Measures

Name	Time	Method
Questionnaire for eating-related distress among patients with advanced cancer (QERD), Care Notebook, FACT-G, anchor questionnaire, ECOG PS, KPS, body weight, objective response rate, disease control rate, progression-free survival, overall survival, adverse events, minimally important difference in QERD, validation of QERD, proportion of cachexia