Vitamin D Supplementation in Pediatrics. Oral or Parenteral! D2 or D3

Phase 4

Not yet recruiting

• Conditions: Vitamin D Deficiency
• Interventions: Dietary Supplement: vitamin D2, vitamin D3

• Registration Number: NCT06176157
• Lead Sponsor: Ain Shams University

Brief Summary

A study will be performed on Vitamin D deficient/ insufficient Egyptian children to compare the efficacy of oral and parenteral forms of Ergocalciferol and cholecalciferol in raising serum 25(OH) D levels in these subjects

Detailed Description

Not available

Study Timeline

• Status Verified: 2023-12
• Study Start: 2023-12
• Study First Submitted: 2023-12-09
• Study First Submitted QC: 2023-12-09
• Last Update Submitted: 2023-12-09
• Study First Posted: 2023-12-19
• Last Update Posted: 2023-12-19
• Primary Completion: 2024-03
• Study Completion: 2024-04

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

• laboratory evidence of vitamin D deficiency or insufficiency without clinical signs of rickets

Exclusion Criteria

• vitamin D or calcium supplementation within the last 6 months before inclusion, patients with diabetes mellitus, chronic liver disease and kidney disease, congenital or rheumatic heart disease, malabsorption syndromes, thyroid disease, juvenile rheumatic diseases, or other bone disorders.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SEQUENTIAL

Arm && Interventions

Group	Intervention	Description
Parenteral vitamin D2 group	vitamin D2, vitamin D3	-
oral vitamin D2 group	vitamin D2, vitamin D3	-
oral vitamin D3 group	vitamin D2, vitamin D3	-
Parenteral vitamin D3 group	vitamin D2, vitamin D3	-

Primary Outcome Measures

Name	Time	Method
serum 25(OH) D level after 1,2,3 months of supplementation	3 months