Preoperative Stellate Ganglion Block Can Cause Enhanced Recovery After Coronary Arteries Bypass Grafting Surgery
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 40
- 试验地点
- 2
- 主要终点
- change in cardiac rhythm
研究概览
简要总结
The effects of SGB on the cardiovascular system remain controversial since the cardiac sympathetic nerves pass through the stellate ganglion. SGB is expected to have an ameliorative effect on impaired coronary circulation and cardiac function and thus to be well suited to the treatment of angina pectoris and myocardial infarction
详细描述
investigators chose left SGB being safer with regards conductivity changes when compared to right SGB, in the present study investigators are trying to examine and compare whether coronary reperfusion in patients undergoing coronary artery bypass grafting who were subject to ultrasound guided left Stellate ganglion block (SGB ) performed in the induction of anesthesia could decrease post cardiopulmonary bypass ischemic changes, pulmonary hypertension and right ventricular dysfunction leading to enhanced recovery.
Place of work: Ain shams university hospitals cardiovascular surgery academy, Cairo, Egypt.
Number and selection of participants:
40 participants, 20 in each group (2 groups).
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Ischemic heart disease patients age above 18 years
排除标准
- •allergy to LA, severe COPD
结局指标
主要结局
change in cardiac rhythm
时间窗: change in cardiac rhythm from base line
incidence of AF or VF(BPM)
change in Ejection Fraction
时间窗: change in Ejection Fraction from base line
Ejection Fraction(%)
change in heart rate
时间窗: change in heart rate from base line
heart rate( bpm )
change in blood pressure
时间窗: change in blood pressure from base line
MAP, Systemic arterial pressure ( mmHg )
次要结局
- effect of preoperative stellate ganglion block on enhanced recovery after coronary arteries bypass grafting surgery(change of troponin level from base line)
研究者
wail abdelaal
assistant professor of anesthesia
Ain Shams University