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Clinical Trials/NCT04439058
NCT04439058
Completed
Not Applicable

Preoperative Stellate Ganglion Block Can Cause Enhanced Recovery After Coronary Arteries Bypass Grafting Surgery

wail abdelaal1 site in 1 country40 target enrollmentJanuary 22, 2020

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Ischemic Heart Disease
Sponsor
wail abdelaal
Enrollment
40
Locations
1
Primary Endpoint
change in cardiac rhythm
Status
Completed
Last Updated
5 years ago

Overview

Brief Summary

The effects of SGB on the cardiovascular system remain controversial since the cardiac sympathetic nerves pass through the stellate ganglion. SGB is expected to have an ameliorative effect on impaired coronary circulation and cardiac function and thus to be well suited to the treatment of angina pectoris and myocardial infarction

Detailed Description

investigators chose left SGB being safer with regards conductivity changes when compared to right SGB, in the present study investigators are trying to examine and compare whether coronary reperfusion in patients undergoing coronary artery bypass grafting who were subject to ultrasound guided left Stellate ganglion block (SGB ) performed in the induction of anesthesia could decrease post cardiopulmonary bypass ischemic changes, pulmonary hypertension and right ventricular dysfunction leading to enhanced recovery. Place of work: Ain shams university hospitals cardiovascular surgery academy, Cairo, Egypt. Number and selection of participants: 40 participants, 20 in each group (2 groups).

Registry
clinicaltrials.gov
Start Date
January 22, 2020
End Date
June 1, 2020
Last Updated
5 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
wail abdelaal
Responsible Party
Sponsor Investigator
Principal Investigator

wail abdelaal

assistant professor of anesthesia

Ain Shams University

Eligibility Criteria

Inclusion Criteria

  • Ischemic heart disease patients age above 18 years

Exclusion Criteria

  • allergy to LA, severe COPD

Outcomes

Primary Outcomes

change in cardiac rhythm

Time Frame: change in cardiac rhythm from base line

incidence of AF or VF(BPM)

change in Ejection Fraction

Time Frame: change in Ejection Fraction from base line

Ejection Fraction(%)

change in heart rate

Time Frame: change in heart rate from base line

heart rate( bpm )

change in blood pressure

Time Frame: change in blood pressure from base line

MAP, Systemic arterial pressure ( mmHg )

Secondary Outcomes

  • effect of preoperative stellate ganglion block on enhanced recovery after coronary arteries bypass grafting surgery(change of troponin level from base line)

Study Sites (1)

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