The Effect of Gender on the Consumption of Pain Medication in Infants Undergoing Craniosynostosis Repair or Untethering of Cord in ITU
- Conditions
- Untethering of CordCraniosynostosis Repair
- Registration Number
- NCT01996163
- Lead Sponsor
- Tel-Aviv Sourasky Medical Center
- Brief Summary
Postoperative pain is a major concern in routine management of children admitted to pediatric intensive care treatment. There are significant negative physiological and psychological ramifications of postoperative pain such as impairment of cardiac function due to tachycardia, restlessness in an intubated patient requiring increase dosage of sedative and paralytic drugs and reduced patient cooperation in the healing process.
The main body of evidence dealing with gender differences in pain perception and treatment stems from studies in the adult and adolescent population as the gonadal hormones have a central role in the way one experiences pain The hypothesis of this study is that there is a difference in the perception of pain, the amount of analgesia used and the response to pain medication between male and female infants undergoing craniosynostosis repair or untethering of cord.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 40
All infants 0-1 year old, admitted to PICU after craniosynostosis repair or untethering of cord.
- Contraindication to analgesic medication
- Infants with neurologic deficits that may hinder the assessment of pain severity such as facial nerve palsy and limb paralysis.
- Ventilated infants.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The average amount per kg of analgesic medications in male and female infants 0-1 year old. The first 24h after surgery The average reduction in pain severity score after receiving analgesics in male and female infants. 24h after surgery
- Secondary Outcome Measures
Name Time Method