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临床试验/NL-OMON53368
NL-OMON53368招募中2 期

Short-term safety and efficacy of ketohexokinase inhibition in patients with hereditary fructose intolerance - Ketohexokinase inhibition in hereditary fructose intolerance

Medisch Universitair Ziekenhuis Maastricht0 个研究点目标入组 8 人开始时间: 待定最近更新:
适应症

试验速览

阶段
2 期
状态
招募中
发起方
入组人数
8

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional

入排标准

年龄范围
18 至 99(—)

入选标准

  • Participants are able to provide signed and dated written informed consent
  • prior to any study specific procedures
  • Use of effective contraception (only applicable to premenopausal women)
  • Aged >= 18 years

排除标准

  • Type 2 diabetes
  • Patients with congestive heart failure and/or severe renal and/or liver
  • insufficiency
  • Uncontrolled hypertension
  • Previous enrolment in a clinical study with an investigational product during
  • the last 3 months or as judged by the investigator which would possibly hamper
  • our study results
  • Use of drugs that inhibit organic anion transporting polypeptide (OATP)
  • transporters (e.g. rifampicin, gemfibrozil, cyclosporine, erythromcyin and
  • clarithromycin)*
  • Subjects who do not want to be informed about unexpected medical findings
  • * Exclusion criterion for HFI patients only.

研究者

发起方
Medisch Universitair Ziekenhuis Maastricht

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