Incidence of COVID-19 Infection in Hemodialysis Patients and Predictors of Disease Complications and Mortality in Assiut University Hospital Hemodialysis Unit: A Cross-Sectional Study
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- COVID-19 Infection in Hemodialysis Patients
- Sponsor
- Assiut University
- Enrollment
- 100
- Primary Endpoint
- Incidence of COVID-19 infection in hemodialysis patients.
- Last Updated
- 4 years ago
Overview
Brief Summary
Dialysis patients have a higher risk of infectious complications including complications from the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) which causes COVID-19. There have been several reports describing the effect of CO¬VID-19 in the dialysis population.
Detailed Description
A report of hospitalized COVID-19 patients from Wuhan, China, showed that hemodialysis patients had worse outcomes compared to controls without kidney failure. In addition, the hemodialysis COVID-19 patients developed serious complications such as shock, acute respiratory distress syndrome (ARDS), arrhythmias, and acute cardiac injury at a higher rate. In a population of hospitalized dialysis patients in New York City, there was a 31% mortality rate and 75% of those who required mechanical ventilation died. These complications are due to some of their underlying comorbidities and difficulties of keeping adequate social distancing as recommended by CDC guidelines. We aim to identify all hemodialysis patients who will be admitted from October 1, 2021 to Septemper 30, 2022. Patients who tested positive for COVID-19 by a polymerase chain reaction (PCR) or highly suspected (CORAD 4-5) according to radiological finding, will be selected and followed until discharge from hospital to determine who will develop complications and who will need ventilatory support. Also, the rate of death will be monitored. Therefore, the current study is aiming to better understand the hemodialysis patients' characteristics profile that makes them susceptible for complications and death.
Investigators
Ahmed Aboelfatouh Tantawy
principal investigator
Assiut University
Eligibility Criteria
Inclusion Criteria
- •All hemodialysis patients who defined as patient receiving maintenance dialysis prior to admission and diagnosed with COVID-19 infection either highly suspicious radiological findings (CORAD 4-5) or proved by PCR for COVID-19.
Exclusion Criteria
- •ALL Patients diagnosed COVID-19 other than hemodialysis patients.
- •Hemodialysis patients with chest infection other than COVID-19.
Outcomes
Primary Outcomes
Incidence of COVID-19 infection in hemodialysis patients.
Time Frame: 1 year
radiological and laboratory findings on MSCT chest \& PCR respectively.