NCT00540956已完成不适用
Descriptive Study Evaluating the Presence and Function of Natural Killer Cells in Elderly Patients With Acute Myeloid Leukemia in First Remission.
Institut Paoli-Calmettes2 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2006年11月1日最近更新:
适应症
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 40
- 试验地点
- 2
- 主要终点
- Evolution of functional natural killer (NK) cells after chemotherapy
研究概览
简要总结
RATIONALE: Studying natural killer cells in samples of blood from patients with cancer may help doctors find out how these cells are effected by chemotherapy.
PURPOSE: This clinical trial is studying natural killer cells in older patients with acute myeloid leukemia.
详细描述
OBJECTIVES:
Primary
- Determine the evolution of functional receptors of natural killer (NK) cells after completion of chemotherapy in elderly patients with acute myeloid leukemia in first remission.
Secondary
- Measure the kinetics of cytotoxic functional recovery of NK cells.
- Determine activation markers of NK cells.
研究设计
- 研究类型
- Interventional
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 65 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •DISEASE CHARACTERISTICS:
- •Diagnosis of acute myeloid leukemia
- •No promyelocytic leukemia
- •No prior therapy
- •PATIENT CHARACTERISTICS:
- •Hemoglobin > 10 g/dL
- •PRIOR CONCURRENT THERAPY:
- •See Disease Characteristics
排除标准
- 未提供
结局指标
主要结局
Evolution of functional natural killer (NK) cells after chemotherapy
次要结局
- Kinetics of NK cells
- Activation markers of NK cells
研究者
研究点 (2)
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