Preoperative Versus Postoperative Quadratous Lunborum Block in Nephrectomy
- Conditions
- Renal SurgeryRegional Blocks
- Interventions
- Other: quadratous lumborum block
- Registration Number
- NCT05860309
- Lead Sponsor
- Ain Shams University
- Brief Summary
A multimodal analgesia regimen is suggested after nephrectomy, although some patients still report agonising pain. Regional anesthesia approaches may improve postoperative pain management and reduce the requirement for opioids after renal surgery.QLB provides early and rapid pain relief
- Detailed Description
In the immediate postoperative period, nerve blocks are considered a type of multimodal analgesia and have recently been proposed as analgesic options for patients undergoing open nephrectomy .
Pain is defined as an unpleasant sensory and emotional experience associated with actual or potential tissue damage. The main barrier to early postoperative ambulation is postoperative pain, which also lengthens hospital stays and raises the risk of respiratory problems and venous thromboembolism. Therefore, strict perioperative pain management can have both immediate and long-term advantages .
QLB provides early and rapid pain relief and allows early ambulation in certain patient populations. Multiple case studies also confirmed the QLB to be a rescue block after different surgical procedures. Complications associated with the performance of abdominal wall blocks are fortunately very rare. However, studies on the effect of anterior QLB on postoperative opioid consumption are scarce .
Regional anesthesia is quickly moving toward using ultrasound guidance as the gold standard. The use of ultrasound has significant advantages over traditional treatments such as nerve stimulation and loss of resistance. The improved safety and efficacy that ultrasound brings to regional anaesthesia will help promote its use and realise the benefits that regional anaesthesia has over general anaesthesia, such as decreased morbidity and mortality, superior postoperative analgesia, cost-effectiveness, decreased postoperative complications and an improved postoperative course .
The aim of the present study is to compare the effectiveness of ultrasound-guided preoperative to postoperative QLB on the postoperative pain scores after Radical nephrectomy.
Recruitment & Eligibility
- Status
- NOT_YET_RECRUITING
- Sex
- All
- Target Recruitment
- 100
-
o Patients aged between 18 - 60 years old.
- Both sexes.
- Physical Status: ASA I and II.
-
o Refusal of procedure or participation in the study .
- Physical status: ASA III or above .
- Infection at site of injection.
- Psychiatric illness .
- CNS Diseases like epilepsy, stroke ...etc.
- History or evidence of coagulopathy .
- Allergies to drug used (Bupivacaine 0.5%).
- Patients who suffered from allergy to local anesthetics .
- Difficult visualization of the anatomy.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description preoperative quadratous lumborum block quadratous lumborum block patients weill recieve preoperative ultrasound guided quadratous lumborum block at lateral position before start of surgery after induction of general anesthesia postoperative quadratous lumborum block quadratous lumborum block patients weill recieve postoperative ultrasound guided quadratous lumborum block at lateral position at the end of surgery before recovery from general anesthesua
- Primary Outcome Measures
Name Time Method The time to first postoperative rescue analgesia. postoperative 24 hours the first time patient ask for analgesia
- Secondary Outcome Measures
Name Time Method total consumption of opioid in first 24 hours first 24 hours postoperatively amount of narcotic needed by patient in first 24 hours after nephrectomy
Trial Locations
- Locations (1)
Ainshams hospitals
🇪🇬Cairo, Egypt