Long Term Effects and of a Pulmonary Rehabilitation Maintenance Program
- Conditions
- Chronic Respiratory Disease
- Registration Number
- NCT03704935
- Lead Sponsor
- University Hospital, Montpellier
- Brief Summary
Chronic respiratory diseases are characterized by a progressive and long term deline. Pulmonary rehabilitation (exercise training and therapeutic education) can improve several disease outcomes like dyspnea, exercise tolerance and health-related quality of life. After an inpatient PR program, maintenance program can stabilize the disease outcomes. However, maintenance program are heterogeneous and long term benefits (\>36 month) have been observed in only one study, which is not feasible in France. A realistic maintenance program as proposed by the French Air+R network (http://airplusr.com/wordpress/) has only demonstrated benefits after 12 month. In addition, the time course of patients may be heterogeneous, with differens clusters that could be influenced by the clinical, functional and systemic determinants. In particular, the cellular muscle microenvironment could be deleterious for the muscle function in patients, caused by a "spill-over" of inflammatory pulmonary molecules in the systemic milieu.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 1000
Not provided
Not provided
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 6 minutes walking distance 10 years 6 minutes walking distance
- Secondary Outcome Measures
Name Time Method health-related quality of life 10 years health-related quality of life : VQ-11 questionnaire
Forced expiratory volume in 1 seconde 10 years Forced expiratory volume in 1 seconde : FEV1
BODE index 10 years BODE index
death 10 years death
Trial Locations
- Locations (1)
Department of clinical Physiology - University Hospital
🇫🇷Montpellier, France