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Clinical Trials/NCT05465772
NCT05465772
Not yet recruiting
Not Applicable

A Study on COVID-19 Patients With Hypertension and/or Kidney Diseases Admitted to Respiratory ICU , Assiut University Hospitals.

Assiut University0 sites180 target enrollmentJuly 2022

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
COVID-19
Sponsor
Assiut University
Enrollment
180
Primary Endpoint
Covid-19 and Hypertension and/or kidney diseases
Status
Not yet recruiting
Last Updated
3 years ago

Overview

Brief Summary

  1. correlation between COVID-19 and Hypertension and/or kidney diseases.
  2. Assess Assess the effect of COVID-19 on patients with Hypertension and/or kidney diseases.
  3. Assess the effect of hypertension and/or kidney diseases on COVID-19 presentation.
  4. Assess the outcome of COVID-19 in patients with hypertension and/or kidney diseases

Detailed Description

The pandemic situation with the emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from China has endangered human lives. Coronavirus disease 2019 (COVID-19) is presented with asymptomatic, mild, or severe pneumonia-like symptoms¹.SARS-CoV-2 has infected humans in all age groups, of all ethnicities, both males and females while spreading through communities at an alarming rate². COVID-19 patients with hypertension, chronic kidney disease, Diabetes, malignancies, HIV, and other comorbidities could develop a life-threatening situation. From the data have reported the characteristics of comorbidities in patients with COVID-19, hypertension was present in nearly 21%, followed by diabetes in nearly 11%, and established cardiovascular disease (CVD) in approximately 7% of patients³. Hypertension posed an increased risk of severe morbidity (approx. 4-fold) and death (approx. 7-fold) from COVID-19 in the presence of multiple comorbidities⁴. The patients with underlying kidney problems are vulnerable to developing COVID-19 infection.The disease also has had consequences on longitudinal management of patients with chronic kidney disease and end stage kidney disease.

Registry
clinicaltrials.gov
Start Date
July 2022
End Date
October 2024
Last Updated
3 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Aya Abdelrhman Kotb Said

Doctor

Assiut University

Eligibility Criteria

Inclusion Criteria

  • Patients above 18 years old. Patients who diagnosed as COVID-19 PCR positive with hypertension and/or kidney diseases.

Exclusion Criteria

  • Young patients below 18 years old. Patients who refused to participate in reseach

Outcomes

Primary Outcomes

Covid-19 and Hypertension and/or kidney diseases

Time Frame: Baseline

Effect of COVID-19 on patients with Hypertension and/or kidney diseases and assess the outcome of COVID-19 in patients with hypertension and/or kidney diseases.

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