A comparative study of effect of intermittent and continuous infusion of cisatracurium in patients undergoing laparoscopic cholecystectomy
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- To compare cisatracurium administration by continuous infusion or intermittent bolus injection in regards to total dose of cisatracurium consumption
研究概览
简要总结
Muscle relaxants are an integral part ofadministering general anaesthesia in patients. Cisatracurium is a newer non-depolarizingskeletal muscle relaxant with an intermediate duration of action. We will be comparing effect of intermittent doses and continuous infusion of cisatracurium in patients undergoing laparoscopic cholecystectomy in regards to total dose of cisatracurium consumption. The study has 2 groups with sample size of 60 patients including both males and females of age 18-65 years and excluding patients who refuse to give consent, laparoscopic surgery converted to open cholecystectomy, pregnant patients, BMI >30, patients with neuromuscular disorder and patients taking drugs which interfere with neuromuscular blockade of the drug.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •Age group between 18-65 years of either gender.
- •ASA grade I and II.
- •Patients scheduled to undergo elective laparoscopic cholecystectomy surgery under general anaesthesia.
排除标准
- •Laparoscopic cholecystectomy converted to open cholecystectomy.
- •Patients with body mass index more than 30 kg/m
- •Pregnant females.
- •Patients taking drugs which interfere with neuromuscular blockade before operation.
- •Patient refusal to give consent.
- •Patients with neuromuscular disorder.
结局指标
主要结局
To compare cisatracurium administration by continuous infusion or intermittent bolus injection in regards to total dose of cisatracurium consumption
时间窗: Intraoperatively every 5 minutes till 30 minutes and every 10 minutes till end of surgery
次要结局
- To compare hemodynamic changes and any side effects during general anaesthesia.(intraoperatively every 5 minutes till 30 minutes and every 10 minutes till end of surgery)