Comparison of Anti-sperm Antibody Levels in Inguinal Hernia Patients Who Undergo Totally Extra-peritoneal and Lichtenstein Repair
Trial Snapshot
- Phase
- Not Applicable
- Sponsor
- Ankara City Hospital Bilkent
- Enrollment
- 160
- Locations
- 1
- Primary Endpoint
- Change from baseline Anti-sperm antibody levels after inguinal hernia surgery
Study Overview
Brief Summary
The purpose of this study is to determine and compare the possible affects of two different inguinal hernia repair technique (TEP and Lichtenstein) on serum ASA levels.
Detailed Description
Antisperm antibody levels are thought to be indirect indicators of spermatic duct injuries. The investigators' ultimate goal is to draw a conclusion about the effect of the type of surgery on spermatic duct integrity. The investigators are going to collect serum samples from inguinal hernia patients before and after surgery. The investigators aim to assess the effect of surgery on antisperm antibody levels of patients who undergo Licthenstein and TEP repair. Preoperative antisperm antibody levels will serve as control levels for each patient group.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- None
Eligibility Criteria
- Ages
- 20 Years to 60 Years (Adult)
- Sex
- Male
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •to accept the terms of the randomization and all study
- •to have unilateral inguinal hernia and set for an inguinal hernia repair
- •to be a father
Exclusion Criteria
- •to have any kind of autoimmune disorders
- •any kind of infertility history
- •to have a history of inguinal and/or genital surgery and/or trauma
Arms & Interventions
TEP group
Patients who undergo totally extraperitoneal hernia repair, TEP Repair.
Intervention: TEP Repair (Procedure)
Lichtenstein group
Patients who undergo Lichtenstein repair.
Intervention: Lichtenstein Repair (Procedure)
Outcomes
Primary Outcomes
Change from baseline Anti-sperm antibody levels after inguinal hernia surgery
Time Frame: Three months for each patient
Samples will be collected before hernia surgery and three months after surgery
Secondary Outcomes
- Comparison of Anti-sperm antibody levels between inguinal hernia patients who have undergone laparoscopic totally extraperitoneal repair and Lichtenstein repair techniques(2 years anticipated)