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临床试验/ISRCTN22146594
ISRCTN22146594已完成未知

Activation of the hypothalamo-pituitary-adrenal axis during cardiac surgery: the effect of surgical stress and cardiopulmonary bypass

niversity of Bristol (UK)0 个研究点目标入组 60 人开始时间: 2012年3月5日最近更新:
适应症

试验速览

阶段
未知
状态
已完成
发起方
入组人数
60

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional

入排标准

性别
All

入选标准

  • Patients having isolated CABG surgery must fulfil all the following criteria:
  • 1. Patient having first time, elective CABG
  • 2. Aged 18 - 80yrs
  • 3. Operation to be carried out using median sternotomy
  • 4. Written informed consent

排除标准

  • Participant may not enter the study if any of the following apply:
  • 1. Emergency operation
  • 2. Previous sternotomy
  • 3. Myocardial Infarction within the last month
  • 4. Concomitant procedure with CABG
  • 5. Left ventricular ejection fraction <30%
  • 6. Operation to be carried out by other incision than median sternotomy (e.g. left thoracotomy)
  • 7. Contraindication to ONCABG or OPCABG (eg. calcified aorta, intramuscular LAD, calcified coronaries, small target vessels)
  • 8. Use of exogenous corticosteroids (including inhalers)
  • 9. Past history of adrenal / pitiutary disease
  • 10. Other major co-morbidities

研究者

发起方
niversity of Bristol (UK)

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