Transdermal Laser Association comparing two treatments of Sclerotherapy for the Treatment of Unesthetic Veins of Lower Limbs: Triple Blind Randomized Clinical Trial

BACKGRAUND: Chemical sclerotherapy is a procedure used to treat varicose veins. Hybrid procedures appear to increase the effectiveness of the treatment. Few publications compare its association with the Nd: YAG laser. The objective of this study was to evaluate the treatment of reticular veins and telangiectasias at the lower limbs with the association of transdermal laser and two sclerosing solutions. PATIENTS AND METHODS: Prospective, randomized, triple-blinded study in 51 lower limbs between January and March 2021, in women aged 18 to 70 years, who presented telangiectasias and reticular veins on the lateral face of the thigh of the lower limbs. Participants were randomized into two treatment groups: Laser Nd:YAG 1064 associated with Sclerotherapy with Glucose 75% and Laser associated with Glucose solution 67.5% + Polidocanol 0.3%. A photographic record was performed prior to treatment and in 30 days for comparison and analysis by two independent vascular surgeons. Complications such as dyschromia, skin ulcers, bruises, matting and phlebitis were also evaluated. RESULTS: The association of laser and sclerotherapy with a 67.5% glucose solution plus 0.3% Polidocanol showed superiority in relation to the use of a transdermal laser with a 75% glucose solution (P<0.05) in the treatment of reticular veins, but with no difference for the treatment of telangiectasias. No unexpected adverse effects were found and 86.3% of patients declared results to be very good or excellent. CONCLUSION: The association of Nd:YAG laser to sclerotherapy with 67.5% Glucose solution + 0.3% Polidocanol was superior for the treatment of reticular veins.