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临床试验/NCT06496802
NCT06496802尚未招募不适用

Prognostic Significance of Preoperative Nutritional Status for Postoperative Acute Kidney Injury in Elderly Patients Undergoing Lung Resection Surgery

Wanmin Liao0 个研究点目标入组 1,880 人开始时间: 2024年7月最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
1,880
主要终点
Postoperative acute kidney injury

研究概览

简要总结

The incidence of postoperative acute kidney injury (AKI) is high in patients undergoing lung resection surgery, especially in the elderly. Early identification of high-risk postoperative AKI patients can help develop prevention and treatment management strategies.

详细描述

The goal of this retrospective study is to investigate the predictive value of preoperative nutritional status, as measured by three scoring systems - the geriatric nutritional risk index (GNRI), prognostic nutritional index (PNI), and controlling nutritional status (CONUT) score - on postoperative AKI in elderly patients under lung resection surgery.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
65 Years 至 100 Years(Older Adult)
性别
All
接受健康志愿者

入选标准

  • aged ≥ 65 years
  • lung resection surgery including:pneumonectomy , bilobectomy , lobectomy, segmentectomy, wedge resection/bullectomy.

排除标准

  • patients with an American Society of Anesthesiologists (ASA) physical status V.
  • those with end-stage renal disease (i.e. a glomerular filtration rate of 15 mL/min/1.73 m2 or receiving haemodialysis).
  • those did not have sufficient data required for nutritional evaluation or AKI evaluation.

结局指标

主要结局

Postoperative acute kidney injury

时间窗: Within 7 days after surgery

In accordance with the KDIGO creatinine criteria: a serum creatinine increases of 26.5 mmol/L within 48 hours or 1.5 times baseline within 7 days after surgery.

次要结局

未报告次要终点

研究者

发起方
Wanmin Liao
申办方类型
Other
责任方
Sponsor Investigator
主要研究者

Wanmin Liao

Professor

Tongji Hospital

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