Changes in Scalp Condition After Using a Moisturizer Containing Celastrol and Cichorium Intybus Root Extract: a Prospective Clinical Trial Using Artificial Intelligence
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 23
- 试验地点
- 1
- 主要终点
- SPI-AI
研究概览
简要总结
The goal of this clinical trial is to evaluate whether a scalp moisturizer containing celastrol and Cichorium intybus root extract can improve scalp condition in adults aged 19 years or older who require scalp moisturization due to dryness, scaling, erythema, or dandruff. The main questions it aims to answer are:
Does once-daily application of the study moisturizer improve scalp condition from baseline to week 4, as assessed by SPI-AI (Scalp Photographic Index-Artificial Intelligence)?
Does the moisturizer improve scalp biophysical parameters (erythema index, stratum corneum hydration, and transepidermal water loss) and patient-reported symptom severity over the 4-week treatment period?
Participants will:
Apply the study moisturizer once daily at bedtime to dry scalp for 4 weeks and rinse it off the following morning using their usual shampoo.
Attend study visits at baseline (week 0), week 2, and week 4 for scalp imaging, biophysical measurements, symptom questionnaires, adherence assessment, and safety monitoring.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 年龄范围
- 19 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age ≥19 years
- •Presence of scalp erythema, dryness, scaling, or dandruff requiring scalp moisturization
排除标准
- •Active infectious scalp dermatoses
- •Use of topical or systemic therapies affecting scalp status within 4 weeks prior to enrollment or during the study period
- •Inability to comply with the study protocol
研究组 & 干预措施
Moisturizer
participants applies the moisturizer once daily to the entire scalp at bedtime
干预措施: Ducray Kertyol P.S.O. Concentrate Cream, Ducray Laboratory, France (Other)
结局指标
主要结局
SPI-AI
时间窗: 4week
Scalp Photographic Index with artificial intelligence
次要结局
- SPI-AI(2week)
- Biophysical parameter(2week)
- Biophysical parameter(4week)
- Biophysical parameter(2 week)
- Biophysical parameter(4 week)
- Patient-reported outcome(2 week)
- Patient-reported outcome(4 week)
研究者
Bo Ri Kim
Assistant professor
Seoul National University Bundang Hospital