Effect of Metoclopramide Versus Sumatriptan for Emergency Department Treatment of Migraine Headache
Phase 2
Completed
- Conditions
- Migraine Disorders
- Interventions
- Drug: Sumatriptan, injection, 6 mg, one timeDrug: metoclopramide, injection,20mg, one time
- Registration Number
- NCT01791400
- Lead Sponsor
- Isfahan University of Medical Sciences
- Brief Summary
The purpose of this study is to determine which drug makes lower migraine headache
- Detailed Description
There are different options to manage benign headache in emergency department.The investigators compared Intravenous metoclopramide with Subcutaneous sumatriptan to relieve pain in emergency department.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 124
Inclusion Criteria
- 20-60 years old and presented with acute headache similar to previous episodes,
- with or without phonophobia,
- photophobia,
- vomiting or nausea.
Exclusion Criteria
- fever or neck stiffness,
- altered mental state,
- pregnancy,
- recent trauma or seizure (within 24 hours),
- focal neurological abnormality on physical examination,
- allergy to metoclopramide,
- hypertension,
- cardiovascular diseases.
Also if the patients had taken a triptan or ergot during the last 24 hours were excluded from the study.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description sumatriptan Sumatriptan, injection, 6 mg, one time Patients who underwent 6 mg sumatriptan subcutaneous one time Metoclopramide metoclopramide, injection,20mg, one time Patients who underwent 20 mg Metoclopramide intravenous one time
- Primary Outcome Measures
Name Time Method pain at one hour after prescription determining pain in Metoclopramide versus sumatriptan groups
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Al-zahra university hospital
🇮🇷Isfahan, Iran, Islamic Republic of