Comparison of two doses of a drug named Clonidine which is added to an injection of other drug used to block nerves of upper limb for surgery on bones
Phase 4
- Conditions
- Health Condition 1: null- any orthopaedic surgery for upper limbs
- Registration Number
- CTRI/2014/02/004398
- Lead Sponsor
- Department of AnaesthesiologyGovernment Medical College Bhavnagar Gujarat India
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 150
Inclusion Criteria
patients posted for upper limb orthopaedic surgery
patients aged between 18 to 40 years
patients of either sex male or female
patients of asa physical status I and II
Exclusion Criteria
patients refusing consent
contraindications to regional anaesthesia
diabetes mellitus
previous nerve injury
history of drug dependence or abuse
history of drug allergy
patients taking analgesics and sedatives
patients on anticoagulants
history of bleeding disorders
any major systemic illness
antenatal females
psychiatric illness
uncooperative patients
inadequate effect requiring supplementation
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method sensory characteristics of block <br/ ><br>onset peak duration post operative analgesia <br/ ><br> <br/ ><br>motor characteristics of block <br/ ><br>onset peak duration <br/ ><br> <br/ ><br>effect on haemodynamic variables like pulse systolic diastolic and mean blood pressure oxygen saturation <br/ ><br> <br/ ><br>sedation score <br/ ><br> <br/ ><br>Timepoint: all parameters to be recorded at 1,3,5,10,15,30 minutes and then at 15 minutes interval till the completion of surgery
- Secondary Outcome Measures
Name Time Method complications to be noted like nerve injury bradycardia and hypotension postoperatively and follow up of patients thereafter in case of nerve injuriesTimepoint: post operatively all parameters to be recorded at half hourly intervals till the offset of sensory and motor blockade and then at 4 hourly intervals for 24 hours <br/ ><br>follow up of patients in opd every 6 months for initial first year and then yearly if they develop nerve injury