Investigating methods of measuring visual field sensitivity in glaucoma

Not Applicable

• Conditions: Investigating peripheral visual sensitivity in people with glaucoma and normally-sighted individuals; Eye Diseases; Glaucoma

• Registration Number: ISRCTN88711666
• Lead Sponsor: Cardiff University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2023-04-21
• Last Update Posted: 18 June 2024
• Study Completion: 2025-10-31

Recruitment & Eligibility

• Status: Ongoing
• Sex: All
• Target Recruitment: 387

Inclusion Criteria

Patients with glaucoma:
1. Diagnosis of Primary Open Angle Glaucoma (POAG) or Normal Tension Glaucoma (NTG) by the hospital eye service
2. Visual field defect consistent with glaucomatous optic nerve appearance.
3. Stable IOP <21 mmHg
4. Refractive error < ±6.00DS and <3.50DC
5. Visual acuity of 6/9 (+0.3 logMAR) or better in the test eye, in the absence of significant corneal or media opacities
6. Age over 40 years

Normally-sighted individuals:
1. No clinical diagnosis of glaucoma or other retinal disease
2. Full visual field
3. Healthy optic disc
4. No family history of glaucoma (first-degree)
5. Refractive error <±6.00DS and <3.50DC
6. Visual acuity of 6/9 (+0.3 logMAR) or better in the test eye, in the absence of significant corneal or media opacities
7. Age over 40 years

Exclusion Criteria

1. Any systemic disease and/or medication which is likely to affect visual performance (e.g. diabetes, thyroid disease)
2. Any ocular disease and/or medication that may affect visual performance (apart from glaucoma)
3. Any previous ocular surgery which may degrade visual performance (e.g. corneal graft, photodynamic therapy)
4. Inability to steadily fixate during the test (e.g. individuals who have nystagmus or macular degeneration)

Study & Design

• Study Type: Observational
• Study Design: Not specified