Prognostic significance of liver stiffness assessed by Fibrosis-4 index in patients with heart failure

Not Applicable

• Conditions: Patients of chronic heart failure

• Registration Number: JPRN-UMIN000040227
• Lead Sponsor: Kumamoto univercity hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2019-12-31
• Study Start: 2020-05-01
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Complete: follow-up complete
• Sex: All
• Target Recruitment: 704

Inclusion Criteria

Not provided

Exclusion Criteria

Patients were excluded for the following reasons: liver disease, severe valvular disease, active infective diseases, history of malignancy, and end stage of renal disease (estimated glomerular filtration rate (eGFR) < 15 ml/min/1.73m).

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Consecutive HF patients referred for hospitalization at Kumamoto University Hospital were registered between 2006 and 2015. We observed cardiovascular outcomes in each type of HF (HF with reduced left ventricular ejection fraction (LVEF) (HFrEF), HF with mid-range LVEF (HFmrEF) and with preserved LVEF (HFpEF)) according to their FIB4 index; group 1 (FIB4 index <1.3), group 2 (FIB4 index: 1.3-2.67) and group 3 (FIB4 index >2.67).