跳至主要内容
临床试验/CTRI/2025/02/080913
CTRI/2025/02/080913尚未招募3 期

Effects of integration of Pilates exercise in dual task training on cognition in midlife obesity A Randomized control trial

Jamia Millia Islamia1 个研究点 分布在 1 个国家目标入组 36 人开始时间: 2025年3月3日最近更新:

试验速览

阶段
3 期
状态
尚未招募
入组人数
36
试验地点
1
主要终点
Cognition( attention using P300 and executive function using Trail Making Test).

研究概览

简要总结

Midlife Obesity has shown direct effects on cognition decline, which could predispose to dementia and Alzheimer disease later in life. Specific correlations with p300 amplitude and latency have been seen in cognition decline in this population. Along with cognition obese individuals have decreased lower limb functional strength. Various strategies have been effective in treating cognitive decline of which dual task training has shown significant differences, but as  dual task involve strength training or aerobic exercise as a motor component along with cognitive task, middle age group show less adherence to these exercise. Whereas Pilates have shown increased adherence in these population along with significant individual effects on cognition level and lower limb strength improvement. Thus integrating Pilates exercise as a motor task in dual task paradigm may result in significant improvements. To the best of my Knowledge no such study has evaluated the effects of pilates with dual task paradigm in obese population.

All the subjects will be informed about the nature, purpose, and possible risks involved in the study and an informed written consent will be taken from them prior to participation. All the subjects will be selected based on the inclusion criteria. Subjects will be familiarised  with the intervention after dividing into either of three groups, Pilates -cog, General physical -cog exercise and control group. Pre and post measures will be taken after two months of intervention. Overall the study will provide the effects of pilates in dual task paradigm compared with general physical-cog exercise and control group on cognition and lower limb functional strength.

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
Participant Blinded

入排标准

年龄范围
35.00 Year(s) 至 50.00 Year(s)(—)
性别
All

入选标准

  • MMSE Score more than 26 MoCA Score more than 25 BMI more than 25 WHR more than 0.80 in males and 0.90 in females IPAQ score with light to moderate active individuals.

排除标准

  • Previous neurological disease Diabetes and hypertension Severe Musculoskeletal problems Patients taking Medication which alter cognition.

结局指标

主要结局

Cognition( attention using P300 and executive function using Trail Making Test).

时间窗: Baseline and at 8 weeks

次要结局

  • Lower limb strength (30s chair sit to stand test)(Functional Mobility ( Tug-cognition test))

研究者

申办方类型
Government funding agency
责任方
Principal Investigator
主要研究者

Dr Majumi M Noohu

Centre for Physiotherapy and Rehabilitation Sciences, Jamia Millia Islamia

研究点 (1)

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