The Impact of Physical Activity on the Postoperative Symptoms, Complications, and Quality of Life Among Lung Cancer Survivors: A Prospective Cohort Study
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 1,050
- 试验地点
- 1
- 主要终点
- The change of quality of life: (EORTC QLQ) core30 (C30)
研究概览
简要总结
The purpose of this study is to examine the impact of physical activity on the postoperative symptoms, complication, and quality of life.
详细描述
Non-small cell lung cancer (NSCLC) survivor is increasing as developing early diagnosis and perioperative management. Despite multidisciplinary treatment, Surgery is the primary treatment option for cure in NSCLC. The patients with lung cancer who underwent surgery have limitation of pulmonary function and high risk of co-morbidities. Perioperative physical activity has been shown to reduce symptoms and prevent complications, improve long term quality of life after surgery. But validated exercise regimen has not been established for lung cancer patients. Therefore, Evidence-based guideline focusing on lung cancer after surgery is needed.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients who are diagnosed with lung cancer
- •Patients who are able to walk with ECOG (Eastern Cooperative Oncology Group) performance status < 1
- •Patients who understand the purpose of this study and provide the written informed consent
排除标准
- •Patients who have difficulty for walking
- •Patients with history of other cancer in the last 3 years
- •Patients with neoadjuvant chemotherapy and/or radiation therapy
- •Patients who are diagnosed with recurrent lung cancer or multiple cancer
- •Foreigner of patients from overseas who are not able regularly participate in this study
结局指标
主要结局
The change of quality of life: (EORTC QLQ) core30 (C30)
时间窗: Before surgery (baseline), and 1, 6, 12, 24, 36, 48, and 60 months after surgery
The change of quality of life is measured using the European Organization for Research Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ) core30 (C30). The scale for quality of life is transformed into a score from 0 to 100, derived by 4-point Likert scale. A higher score represents a higher level of quality of life.
次要结局
- Postoperative pulmonary complications(Within 30 days after surgery)
- The change of symptom(Before surgery (baseline), and 1, 6, 12, 24, 36, 48, and 60 months after surgery)