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Clinical Trials/NCT04631432
NCT04631432
Completed
N/A

Choice Switching and Autism

Technion, Israel Institute of Technology1 site in 1 country114 target enrollmentJanuary 1, 2021

Overview

Phase
N/A
Intervention
Not specified
Conditions
Autism Spectrum Disorder (ASD)
Sponsor
Technion, Israel Institute of Technology
Enrollment
114
Locations
1
Primary Endpoint
Mean run size
Status
Completed
Last Updated
4 years ago

Overview

Brief Summary

The study aims to replicate and clarify a recently observed phenomenon whereby individuals with Autism Spectrum Disorder (ASD) switch between options in a repeated task to a greater extent than healthy controls do. In a meta-analysis a large effect size was found (.37) yet because the effect was noisy in different studies it was not statistically significant. The investigators seek to first examine a very large population through an Internet mediated platform. The sample size will be about the size of all of the previous studies that examined this issue together. Secondly, the investigators wish to understand the discrepancy between this choice switching phenomenon and the recorded tendency of ASD individuals to avoid changing choices. First, the investigators will administer the task in which the effect was found (the Iowa Gambling task) for a longer duration than previously and evaluate whether ASD individuals show increased choice switching in the first blocks of trials but reduced switching following more experience. Secondly, the investigators will administer an additional block of trials without feedback in which participants will not be able to go through a learning process. The investigators predict that this will reduce (and possible flip) the tendency of individuals with ASD to switch choices more often.

Registry
clinicaltrials.gov
Start Date
January 1, 2021
End Date
September 13, 2021
Last Updated
4 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Prof. Eldad Yechiam

Professor

Technion, Israel Institute of Technology

Eligibility Criteria

Inclusion Criteria

  • ASD group - Diagnosed with ASD
  • Control - No ASD diagnosis: within age and education range of the ASD group.

Exclusion Criteria

  • Demographics: Under 18 years of age.
  • Mental health: self reported brain injury and neurological disorder (besides autism).

Outcomes

Primary Outcomes

Mean run size

Time Frame: Through study completion, an average of 1 year

Number of consecutive selections from the same deck (across trials and in different blocks).

Advantageous selections

Time Frame: Through study completion, an average of 1 year

Percentage of advantageous selections(across trials and in different blocks).

Study Sites (1)

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