Tulobuterol Patch in Pediatric Patients Undergoing Tonsillectomy
Not Applicable
Completed
- Conditions
- Tonsillar Hypertrophy
- Interventions
- Drug: Placebo transdermal patch
- Registration Number
- NCT04057469
- Lead Sponsor
- Seoul National University Hospital
- Brief Summary
* Tonsillectomy is a common pediatric procedure for the treatment of sleep-disordered breathing and chronic tonsillitis. Up to half of children having this procedure experience a perioperative respiratory adverse event.
* We tried to determine whether tulobuterol patch (transdermal bronchodilator) premedication decreases the risk of perioperative respiratory adverse events in children undergoing anesthesia for tonsillectomy.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 182
Inclusion Criteria
- pediatric patients undergoing tonsillectomy
Exclusion Criteria
- recent upper respiratory infection (2weeks)
- Allergy to tulobuterol patch
- Patients receiving catecholamine (epinephrine, isoproterenol)
- hyperthyroidism
- hypertension
- cardiac disease
- Diabetes melitus
- atopic dermatitis
- Asthma
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Placebo Placebo transdermal patch - Tulobuterol patch Tulobuterol Hydrochloride -
- Primary Outcome Measures
Name Time Method perioperative respiratory complication from anesthetic induction to postanesthesia care unit discharge, an average of 3 hours laryngospasm, bronchospasm, oxygen desaturation, airway obstruction, severe coughing, postoperative stridor
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (4)
Seoul National University Hospital
🇰🇷Seoul, Korea, Republic of
Hyun-Joo Kim
🇰🇷Seoul, Korea, Republic of
Jin-Kyung Kim
🇰🇷Seoul, Korea, Republic of
Chung-Ang University Hospital
🇰🇷Seoul, Korea, Republic of