comparative evaluation of oral voriconazole and oral ketoconazole in severe fungal keratitis
Phase 4
- Conditions
- Health Condition 1: null- severe fungal keratitisHealth Condition 2: H169- Unspecified keratitis
- Registration Number
- CTRI/2016/07/007103
- Lead Sponsor
- DR R P Centre AIIMS New Delhi
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 40
Inclusion Criteria
SEVERE FUNGAL KERATITIS
EVIDENCE OF FUNGI IN SMEAR OR CULTURE
VN <3/60
CONSENT
WILLING TO BE TREATED AS INPATIENT AND RETURN IN 3 DAYS TILL EPITHELIZATIO
Exclusion Criteria
EVIDENCE OF BACTERIA OR ACANTHAMOEBA ON STAIN
EVIDENCE OF HERPETIC KERATITIS
B/L OR PERFORATED ULCER
H/O PREVIOUS OCULAR SX
PREGNANCY
IMMMUNOCOMPROMISED
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method VISUAL ACUITYTimepoint: DAY3,7,14,21,28,3 MNTHS
- Secondary Outcome Measures
Name Time Method TEAR FILM CONCENTRATION OF DRUG SENSITIVITY AGENTS <br/ ><br>DRUG SENSITIVITY PATTERNTimepoint: DAY7,14,21